Results 131 to 140 of about 262,700 (294)

Weathering performance of particleboards manufactured from blends of forest residues with red pine (Pinus brutia) wood

open access: yesMaderas: Ciencia y Tecnología, 2014
Red pine cone and barks combined with red pine wood particles in various proportions were used as the raw materials for one and three layered experimental particleboard manufacturing in laboratory conditions.
H. Turgut Sahin, M. Burak Arslan
doaj  

Evaluation of OSB panels using residual wood with low contents of castor oil polyurethane resin

open access: yesMaderas: Ciencia y Tecnología
The use of residues from human activities has been currently gaining ground in the national and international markets, aiming toward the production of more sustainable materials that are less aggressive to the environment.
Guilherme Barbirato   +4 more
doaj   +1 more source

A Nanobody‐LNP Platform for Targeting and Relicensing Dendritic Cells for Potent Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Plastin‐2 (PLS2) is identified as a dual‐function receptor on DCs that mediates both nanoparticle uptake and immunomodulation. A nanobody‐LNP platform is engineered to integrate antigen delivery with relicensing DCs. The therapeutic strategy elicits potent anti‐tumor T cell responses and leads to significant inhibition of established tumors in vivo ...
Shugang Qin   +9 more
wiley   +1 more source

Weathering performance of particleboards manufactured from blends of forest residues with Red pine (Pinus brutia) wood

open access: yesMaderas: Ciencia y Tecnología, 2011
Red pine cone and barks combined with red pine wood particles in various proportions were used as the raw materials for one and three layered experimental particleboard manufacturing in laboratory conditions.
H Turgut Sahin, M Burak Arslan
doaj  

NQO1‐Mediated Anoikis Resistance and Immune Evasion Define a High‐Risk Multi‐Omic Subtype for Precision Management of T1 High‐Grade Bladder Cancer

open access: yesAdvanced Science, EarlyView.
Multi‐omic profiling of T1 high‐grade bladder cancer identifies a high‐risk subtype (T1HG1) driven by NQO1, which couples anoikis resistance with immune evasion. NQO1 orchestrates macrophage–T cell crosstalk suppression via CXCL9 modulation. Pharmacological NQO1 inhibition with skullcapflavone II enhances cisplatin efficacy, representing a promising ...
Bin Guo   +20 more
wiley   +1 more source

A Hydrogen‐Releasing Nanozyme Engineers a Mitochondrial ROS Amplifier for Self‐Sustaining Catalytic Immunotherapy

open access: yesAdvanced Science, EarlyView.
We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi   +12 more
wiley   +1 more source

A Novel CsYABBY3‐CsAS1 Feedback Loop Coordinates Trichome Differentiation and Cannabinoid Biosynthesis in Cannabis sativa L.

open access: yesAdvanced Science, EarlyView.
A novel transcriptional module involving CsYABBY3 and CsAS1 is identified to regulate cannabinoid biosynthesis and trichome development. These factors mutually activate each other and form a protein complex via a conserved residue, acting synergistically to amplify metabolic flux through a coordinate feed‐forward mechanism.
Xuewen Zhu   +18 more
wiley   +1 more source

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li   +13 more
wiley   +1 more source

Autonomous and Continuous Atmospheric Water Harvesting Using Modified Wood

open access: yesAdvanced Science, EarlyView.
A rigid, hydroxyl‐rich wood skeleton with graded channels is used as a multifunctional host to co‐incorporate a PNipam/PAA network and LiCl, creating a high‐performance sorbent for atmospheric water harvesting. The composite achieves rapid sorption, efficient low‐temperature desorption, and stable cycling, enabling a solar‐powered device with a high ...
Shiheng He   +7 more
wiley   +1 more source

ANXA2‐mediated Phagocytosis Generates AR+ Macrophages to Confer Enzalutamide Resistance in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...
Yong Luo   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy