Chemical profiling and evaluation of in vitro antibacterial and antibiotic synergistic activities of Cleistanthus bracteosus Jabl. from Malaysian rainforests. [PDF]
Dassanayake MK +6 more
europepmc +1 more source
Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch +6 more
wiley +1 more source
The Effect of Natural Colourants in Woad (<i>Isatis tinctorum</i> L.) on the Dyeing Properties of Oak and Poplar Wood. [PDF]
Kucharczyk N, Szadkowski J.
europepmc +1 more source
TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu +9 more
wiley +1 more source
Unravelling the Secret of Phantom Phenotypes in Macrolichens: Insights From Cladonia bellidiflora Complex. [PDF]
Konečná E +3 more
europepmc +1 more source
TSTScope is an interpretable AI framework that integrates single‐cell transcriptomes with TCR information through curated gene‐program constraints. By linking receptor context to functional T cell states, it reveals response‐associated tumor‐specific T cell programs in lung cancer immunotherapy cohorts and defines an MPR score associated with ...
Shiwei Cao +8 more
wiley +1 more source
Recent Advances and Sustainability Perspectives of Biobased Wood Panel Adhesives: Toward Cleaner and Formaldehyde-Free Wood Products. [PDF]
Movahed SG +13 more
europepmc +1 more source
Guided by a Random Forest model, a π–π‐driven ordered stacking strategy deploys functionally distinct substructures to restrict chain segment motion and increase free volume, while preserving the intermolecular interactions that maintain structural integrity.
Zi‐Meng Xu +10 more
wiley +1 more source
A new application of bacterial cellulose in textiles and fashion: using Kombucha-derived biofilm to remove dye from polluted water. [PDF]
Wood J, Verran J, Randviir E, Redfern J.
europepmc +1 more source
Schematic illustration of development of experimental datasets and algorithm models, screening and preparation of the scaffolds and their applications in vivo. ABSTRACT Bone defects require materials with osteogenic, neurogenic, and angiogenic activity, yet designing such materials within high‐dimensional compositional spaces remains challenging. Here,
Kunlu Lin +9 more
wiley +1 more source

