Results 201 to 210 of about 25,492 (258)

Loss of SHP1 in Spinal Astrocytes Triggers T‐Lymphocyte Infiltration and Nociceptive Hypersensitivity

Advanced Science, EarlyView.
Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi, Lin Yang, Kang‐Li Wang, Hui‐Zhu Liu, Rui‐Ying Chen, Min Su, Xiao Xiao, Yu‐Qiu Zhang   +7 more
wiley   +1 more source

The Rana sylvatica skin-secreted antimicrobial peptide (AMP) gene repertoire highlights broader patterns in anuran AMP evolution. [PDF]

Sci Rep
Douglas AJ, Katzenback BA.
europepmc   +1 more source

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +1 more source

Remote photoplethysmography for cardiorespiratory self-monitoring: A qualitative study of usability, convenience, and patient confidence. [PDF]

Digit Health
Wood KV, Moore A, Ahmad M, Bostanci DN.
europepmc   +1 more source

Macrogenetic Alignment in Ecological Strategies Better Interprets Assembly Processes Than Pre-Determined Functional Groupings. [PDF]

Ecol Lett
Rossetto M, Dimon R, Kooyman RM, Wilson PD, Yap JS.   +4 more
europepmc   +1 more source

The spirit of the woods : illustrated by coloured engravings

Rebecca. Hey, Andrew Spottiswoode
openaire   +2 more sources

Multi-disciplinary diagnosis and management of verrucous venous malformation of the right knee: a case report. [PDF]

Front Radiol
H V, Madke B, Sharma P, Singh A, Mittal A, Tiwari VV.   +5 more
europepmc   +1 more source

Cooking, cleaning, and tossing: high-resolution analysis of domestic activities at the Mid-Neolithic site of Molino Casarotto (Vicenza, NE Italy). [PDF]

Archaeol Anthropol Sci
Cristiano N, Gregorio DS, Federico P.
europepmc   +1 more source

Polyethylene Shows No Concerning Evidence of Material Changes or Stress Cracking After Exposure to Chlorhexidine Gluconate and Povidone-Iodine Irrigation Solutions. [PDF]

J Orthop Res
Abdel Khalik H, Chakrabarti MO, Marway HS, Thompson MR, Puri L, Tate I, Wood TJ.   +6 more
europepmc   +1 more source

The About 100 Million Years Old Enigmatic "Beak Larva" Is a Weird Click Beetle Relative. [PDF]

Insects
Linhart SJ, Haug C, Hammel JU, Saß S, Haug JT.   +4 more
europepmc   +1 more source