Results 31 to 40 of about 1,140,494 (284)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
A colour assessment methodology for oak wood [PDF]
Annals of Forest Science, 2012 Context Customers have limited tolerances for colour differences between oak wood elements in parquetry or furniture, whereas manufacturers are in need of an objective method to communicate possible differences in their products.
Defoirdt, +5 more
openaire +1 more source
Colour normalisation to reduce inter-patient and intra-patient variability in microaneurysm detection in colour retinal images [PDF]
, 2005 Images of the human retina vary considerably in their appearance depending on the skin pigmentation (amount of melanin) of the subject. Some form of normalisation of colour in retinal images is required for automated analysis of images if good ...
Cornforth, D.J. +2 more
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
BioResources, 2015 The purpose of this investigation was to evaluate the effect of acid and alkaline treatment of pine wood on photodegradation. The work presented here deals with changes in the wood colour and infrared spectrum caused by UV light.
Magdalena Zborowska +4 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Maderas: Ciencia y Tecnología, 2001 The colorimetry theory for the CIELab system today allows us to compute the chromatic coordinates of the raw timber colour along the wood - chain industry. The wood industry is nd strongly behind in such areas. Progress in the wood appearance description
Gérard Janin +5 more
doaj
COLOUR AND DIMENSIONAL MODIFICATIONS OF SOLID WOOD PANELS MADE FROM HEAT-TREATED SPRUCE WOOD AFTER THREE MONTHS OF OUTDOOR EXPOSURE [PDF]
Pro Ligno, 2014 The paper presents the results of an experimental research performed with spruce wood (Picea abies L.), originating from mature trees and thinnings cut from the same forest parcel from the Stroesti-Arges region in Romania.
Cristina Marinela OLĂRESCU +2 more
doaj