Results 41 to 50 of about 797,231 (296)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Predicting the morphological characteristics and basic density of Eucalyptus wood using the NIRS technique [PDF]

, 2009
This research aimed to apply the near infrared spectroscopy technique (NIRS) for fast prediction of basic density and morphological characteristics of wood fibers in Eucalyptus clones.
Gherardi Hein, Paulo Ricardo, Moreira da Silva, Jose Reinaldo, Tarcisio Lima, Jose, Trugilho, Paulo Fernando, Viana, Livia Cassia   +4 more
core  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

CLONAL AND PLANTING DENSITY EFFECTS ON SOME PROPERTIES OF RUBBER WOOD (HEVEA BRASILIENSIS MUELL. ARG.)

BioResources, 2011
Inter-clonal and intra-clonal wood properties and their variations from pith to bark were evaluated for wood density and anatomical features on rubber wood (Hevea brasiliensis Muell.
Hamid Reza Naji,, Mohd. Hamami Sahri,, Tadashi Nobuchi,, Edi Suhaimi Bakar   +3 more
doaj  

Effects of potassium/sodium fertilization and water availability on wood properties of Eucalyptus grandis trees [PDF]

, 2019
In Brazil. most Eucalyptus plantations are located in regions experiencing periods of water shortage where fertilizers such as potassium (K) are intensively used to achieve high productivity. Recently.
Chaix, Gilles, Chambi Legoas, Roger, Tomazello Filho, Mario   +2 more
core  

Diversity of decay resistance strategies of durable tropical woods species: Bocoa prouacencsis Aublet, Vouacapoua americana Aublet, Inga alba (Sw.) Wild [PDF]

, 2014
International audienceThe study of decay resistance in wood is of interest for wood end-users but also for the global carbon balance since wood biodegradation is a key driver of forest ecosystem functioning through its impacts on carbon and nutrient ...
Amusant, Nadine, Beauchêne, Jacques, Nigg, M, Thibaut, Bernard   +3 more
core   +3 more sources

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

Age trends and within-site effects in wood density and radial growth in Quercus faginea mature trees

Forest Systems, 2016
Aim of the study: This paper aims to valorize the wood of Quercus faginea Lam. for high quality end uses (e.g. furniture) by studying growth and quality properties using mature trees.
Vicelina B. Sousa, José-Luís Louzada, Helena Pereira   +2 more
doaj   +1 more source

Eco-friendly approach and potential biodegradable polymer matrix for WPC composite materials in outdoor application [PDF]

, 2019
Blends based on high density polyethylene (HDPE) and poly(lactic) acid (PLA) with different ratios of both polymers were produced: a blend with equal amounts of HDPE and PLA, hence 50 wt.% each, proved to be a useful compromise, allowing a high amount of
Massardier, Valerie, Quitadamo, Alessia, Valente, Marco   +2 more
core   +1 more source