Results 41 to 50 of about 801,212 (294)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Wood density for forest conservation: towards improvement of biomass and carbon stocks in tropical regions [PDF]

, 2015
The assessment of forest biomass has important consequences for climate-related policies, including conservation and activities related to deforestation and forest degradation.
Birigazzi, Luca, Chiti, Tommaso, Donegan, Emily, Gamarra, Javier Garcia Perez, Henry, Matieu, Murillo, Julian, Picard, Nicolas, Saint-André, Laurent, Sola, Gael, Vieilledent, Ghislain   +9 more
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Physical Properties of Wood in Poplar Clones ’I-214’ and ’S1-8’

Drvna Industrija, 2016
Physical properties play an important role in predicting the quality of wood raw material. Variation in wood density and wood shrinkage of two different poplar clones cultivated on plantation “Drnje” near Koprivnica in Croatia was measured. One of poplar
Iva Ištok, Tomislav Sedlar, Bogoslav Šefc, Tomislav Sinković, Tomica Perković   +4 more
doaj   +1 more source

Impact of Wetting–Drying Cycles on the Mechanical Properties and Microstructure of Wood Waste–Gypsum Composites [PDF]

, 2019
Large amounts of wood waste are generated each year in the world. In an attempt to identify a good recovery option for those residues, wood waste from construction and demolition works were used as raw materials in gypsum plasters.
Morales Conde, María Jesús, Pedreño-Rojas, M. Alejandro, Pérez Gálvez, Filomena, Rubio de Hita, Paloma   +3 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The Age and Density of Ancient and Modern Oak Wood in Streams and Sediments [PDF]

, 2003
Large wood of oak trees (Quercus spp.) has resided in the streams and sediments of north Missouri, USA for many thousands of years. This wood affords the opportunity to compare a chronosequence of differences in wood density over a very long period.
Guyette, Richard P. (Richard Paul), Stambaugh, Michael C. (Michael Charles)   +1 more
core   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Plastics: physical-and-mechanical properties and biodegradable potential [PDF]

, 2020
Introduction. Processing agricultural waste into plant biodegradable plastics is a promising way for its recycling. This work featured the main physical-and-mechanical properties of plant plastics without adhesive substances obtained from millet husk and
Artyemov, A. V., Buryndin, V. G., Glukhikh, V. V., Krivonogov, P. S., Krivonogova, A. S., Savinovskih, A. V.   +5 more
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source