Results 221 to 230 of about 1,030,908 (254)

Integrated Multi‐Omics Reveals Cellular States and Microenvironmental Remodeling in Coexisting DCIS and IDC

Advanced Science, EarlyView.
Coexisting DCIS and IDC samples are profiled using spatial transcriptomics, single‐cell RNA sequencing, and single‐cell DNA sequencing. Integrative multi‐omics analysis reveals distinct malignant epithelial and microenvironmental features between DCIS and IDC, which are further validated using Xenium and multiplex immunohistochemistry.
Ning Zhang, Tong Wan, Siyue Zhang, Yunzhen Jiang, Peng Su, Jixin Liu, Zhitong Chen, Jie Hao, Haoyu Wang, Bing Chen, Wenjing Zhao, Lijuan Wang, Tao Xing, Qihuang Zhang, Ulf Schmitz, Zhiyong Ding, Nicola Crosetto, Bingqiang Liu, Qifeng Yang   +18 more
wiley   +1 more source

Evaluating urban oriental plane wood as a tonewood: effects of solvent extraction on acoustic performance. [PDF]

Sci Rep
Roohnia M.
europepmc   +1 more source

Transport–Reaction–Signal Coupling in Lateral Flow Assays for Next‐Generation Point‐of‐Care Diagnostics

Advanced Science, EarlyView.
Lateral flow assays are evolving into interdisciplinary, system‐level sensing platforms. Recent innovations are deconstructed through coupled phases of mass transfer, reaction, and signal transduction, revealing interdependence across porous materials, interfacial chemistry, nanolabels, readout devices, and data‐enabled analysis.
Yan Pan, Yuewei Li, Chao Mi, Zhengwen Yang, Lana McClements, Steven J. Langford, Jiayan Liao   +6 more
wiley   +1 more source

Wood Hemicellulose-Based Spray-Dried Microencapsulation of a Lytic Bacteriophage Preserves Phage Viability and Improves Control of the Bacterial Wilt Pathogen Ralstonia solanacearum. [PDF]

Microb Biotechnol
Negroni AM, Hendrich CG, Ho MT, Yousefvand A, Friman VP.   +4 more
europepmc   +1 more source

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

Advanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu, Yingyu Zhang, Xianwei Zhang, Mengxin Zhang, Fei Zhang, Jushan Sun, Yahui Yang, Kangbo Liu, Peng Wang, Shuying Luo, Wancun Zhang   +10 more
wiley   +1 more source

Transfer RNA‐Derived Small RNA‐5’tiRNAGln Drives HNRNPC Phase Separation to Promote Breast Cancer Bone Metastasis by Regulating IGF1R

Advanced Science, EarlyView.
This study reveals that 5'tiRNA‐Gln interacts with hnRNPC to promote IGF1R liquid‐liquid phase separation, which drives ERK1/2 signaling activation, EMT, and breast cancer bone metastasis. These findings highlight a novel mechanism of breast cancer bone metastasis and potential therapeutic target in metastatic breast cancer.
Bingnan Wang, Dongsong Liu, Xiaozhi Fan, Jiale Fan, Xuesi liu, Yu Wang, Zixin Wang, Mo Cheng, Ping Zhou, Wangjun Yan   +9 more
wiley   +1 more source

Polyelectrolyte Complex/MMT Hybrid for SPI/WE Adhesives with Balanced Flame Retardancy and Shear Strength. [PDF]

Gels
Yang H, Luo Y, Ding S, Wu C, Zhang T.
europepmc   +1 more source

Computational and Data‐Driven Strategies for Lignocellulosic Biomass Valorization: From Multiscale Modeling to Digitalized Biorefinery Design

Advanced Science, EarlyView.
This Review critically connects structural recalcitrance, molecular modeling, solvent and catalyst design, pyrolysis, machine learning, reactor simulation, and FAIR digital infrastructure. Emphasis is placed on experimentally validated information transfer across scales, uncertainty and applicability domains, and the recycle, durability, techno ...
Abdullahi Bello Umar, Jiaxian Zheng, Xiangfeng Lin, Hongwu Liao, Haoqian Xu, Yufei Huang, Zaharaddeen Nasiru Garba, Adamu Uzairu, Weiwei Zhao, Zhanhui Yuan   +9 more
wiley   +1 more source

Loose and Pelleted Natural Litter: Effects of Composition and Formulation on Litter Quality and Broiler Footpad Health. [PDF]

Animals (Basel)
Knežević S, Pajić M, Živkov Baloš M, Đurđević B, Prodanov-Radulović J, Ružić Z, Vidaković Knežević S.   +6 more
europepmc   +1 more source

Rhizodeposition Drives One Third of Belowground Carbon Input in Agroecosystems

Advanced Science, EarlyView.
This study quantifies photosynthesized C allocation in the plant–soil system across six crop types: barley, wheat, maize, rice, legumes and grasses. It reports C partitioning into shoot respiration, shoot‐C, root‐C, net rhizodeposition and root‐derived CO2, providing standardized percentage averages and GPP‐derived absolute values as a robust baseline ...
Zhengjun Yan, Yuan Wen, Jie Zhou, Yakov Kuzyakov, Damien Beillouin, Johannes Lehmann, Yadong Yang, Yiqi Luo, Pete Smith, Zhaohai Zeng, Huadong Zang   +10 more
wiley   +1 more source