Results 201 to 210 of about 2,031,469 (352)

Chromatin Organization Governs Transcriptional Response and Plasticity of Cancer Stem Cells

Advanced Science, EarlyView.
Through a combination of transcriptomic and histone mapping studies integrated with chromatin imaging, we define how chromatin organization in nanoscale packing domains fine tunes the plasticity of cancer stem cells (CSCs) driving evasion from and survival after chemotherapy.
Yinu Wang, Jane Frederick, Karla Isabel Medina, Elizabeth Thomas Bartom, Luay Matthew Almassalha, Yaqi Zhang, Greta Wodarcyk, Hao Huang, I Chae Ye, Ruyi Gong, Cody Levi Dunton, Alex Duval, Paola Carrillo Gonzalez, Joshua Pritchard, John Carinato, Iuliia Topchu, Junzui Li, Zhe Ji, Mazhar Adli, Vadim Backman, Daniela Matei   +20 more
wiley   +1 more source

Sustainable decision making for chemical process systems via dimensionality reduction of many objective problems

AIChE Journal, Volume 69, Issue 2, February 2023., 2023
Abstract Recent global events and the rise of sustainable investing have made clear that the chemical and energy industry must consider sustainability goals beyond profit maximization to remain competitive. Multiobjective optimization provides an ideal framework for analyzing sustainability tradeoffs, but when four or more objectives are considered ...
Justin M. Russell, Andrew Allman
wiley   +1 more source

Improving word embeddings in Portuguese: increasing accuracy while reducing the size of the corpus. [PDF]

PeerJ Comput Sci, 2022
Pinto JP, Viana P, Teixeira I, Andrade M.   +3 more
europepmc   +1 more source

A Word-Embedding-based Sense Index for Regular Polysemy Representation [PDF]

, 2015
Marco Del Tredici, Núria Bel
openalex   +1 more source

Word Embeddings as Statistical Estimators

Sankhya B
Word embeddings are a fundamental tool in natural language processing. Currently, word embedding methods are evaluated on the basis of empirical performance on benchmark data sets, and there is a lack of rigorous understanding of their theoretical properties.
Neil Dey, Matthew Singer, Jonathan P. Williams, Srijan Sengupta   +3 more
openaire   +2 more sources

Advancing the Identification of Bioactive Molecules and the Construction of a Synergistic Drug Delivery System in Combating Lung Injury

Advanced Science, EarlyView.
Traditional Chinese Medicine (TCM), while holistic and historically esteemed, faces challenges in “miracle cures” due to slow onset, long cycles, and difficulty controlling quality. This study obtains the active ingredients, glabridin (GLA) and puerarin (PUE), from Ge‐Gen Decoction (GGD), developing a safe and effective drug delivery system, GLA‐PUE ...
Jianhong Qi, Yanxia Wang, Huan Chen, Kaitian Wu, Pei Zhou, Yue Dou, Bingqi Xiong, Wei Zhou   +7 more
wiley   +1 more source

Visualization of medical concepts represented using word embeddings: a scoping review. [PDF]

BMC Med Inform Decis Mak, 2022
Oubenali N, Messaoud S, Filiot A, Lamer A, Andrey P.   +4 more
europepmc   +1 more source

A Computational Model to Disentangle Semantic Information Embedded in Word Association Norms

, 2008
Javier Borge, Àlex Arenas
openalex   +2 more sources

Supervised Phrase Table Triangulation with Neural Word Embeddings for Low-Resource Languages [PDF]

, 2015
Tomer Levinboim, David Chiang
openalex   +1 more source

AKT1 Phosphorylates FDX1 to Promote Cuproptosis Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study demonstrates that copper activates the AKT signaling pathway, which inhibits ferredoxin‐1 (FDX1), a key regulator of cuproptosis. AKT1‐mediated FDX1 phosphorylation not only abrogates FDX1‐induced cuproptosis and aerobic respiration but also promotes glycolysis.
Zicheng Sun, Huazhen Xu, Guanming Lu, Ciqiu Yang, Xinya Gao, Jing Zhang, Xin Liu, Yongcheng Chen, Kun Wang, Jianping Guo, Jie Li   +10 more
wiley   +1 more source