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ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao +5 more
wiley +1 more source
Nasopharyngeal swab transcriptomics identifies divergent molecular signatures in adenoid hypertrophy and allergic rhinitis comorbidity. [PDF]
Pu S +8 more
europepmc +1 more source
Integrated Transcriptomic Profiling Reveals Distinct and Overlapping Transcriptional Responses and Regulatory Pathways Mediated by Salicylic Acid, Jasmonic Acid, and Abscisic Acid in Lotus (<i>Nelumbo nucifera</i>). [PDF]
Xu J, Yang Z, Yang J, Meng Y, Liu X.
europepmc +1 more source
Anaerobic mono-digestion of wheat straw in a three-stage semi-continuous system inspired by a beetle larva gut. [PDF]
Schroeder BG +6 more
europepmc +1 more source
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