Results 91 to 100 of about 498,510 (259)

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Typology of Work-Family Balance Among Middle-Aged and Older Japanese Adults. [PDF]

open access: yesFront Psychol, 2022
Tomida M   +6 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Childbearing and Work-Family Balance among Contemporary Russian Women

open access: yesFinnish Yearbook of Population Research, 2010
There are contrasting views on how gender equality affects fertility in contemporary European societies. This article discusses the Russian situation by asking how tensions in the contemporary gender system relate to reproductive decision-making and ...
Anna Temkina
doaj  

A bibliometric analysis of work–family balance: trends, themes, and future directions (2000–2024)

open access: yesCogent Business & Management
Despite the growing importance of work-family balance (WFB), the field still lacks large-scale, quantitative, and replicable review studies. To fill this gap, this paper adopts a bibliometric approach to analyze 921 relevant articles published between ...
Yunshi Fang   +3 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

The Effect of Work–Family Conflict and Family–Work Conflict on Job Satisfaction with Work–Life Balance as a Mediating Variable at PT. Wahyu Wisata Mandalika

open access: yesDanadyaksa
This study examines the effects of Work–Family Conflict and Family–Work Conflict on Job Satisfaction, with Work–Life Balance as a mediating variable among employees of PT. Wahyu Wisata Mandalika.
Maya Okyantari, Mukmin Suryatni
doaj   +1 more source

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