Results 101 to 110 of about 370,298 (295)
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Work-family enrichment: A potential buffer of inflammation among black adults? [PDF]
Brain Behav Immun Health, 2022 Thomas ND +5 more
europepmc +1 more source
Work-family conflict and enrichment : a study of college coaches
, 2008 textThe current work-family literature strongly emphasizes the conflict between the multiple roles that workers and parents assume. This conflict literature leaves readers with the impression that individuals are experiencing stress to a level that ...
Schenewark, Jarrod Denman
core
Role of work-family enrichment in improving job satisfaction [PDF]
, 2014 The role of work-family enrichment in improving job satisfaction has been given little attention. In this study a mediation model was tested which includes work-family enrichment as the mediator, job characteristics (job autonomy and job involvement) as ...
Omar, Zoharah +2 more
core +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Work to Family Enrichment as Mediator between Organizational Support and Employees’ Performance [PDF]
Pakistan Journal of Commerce and Social Sciences, 2018 This study investigates the relationship between work to family organizational support and employees’ performance, mediated by work to family enrichment.
Aneel Kumar (Corresponding author) +2 more
doaj
How Family Supportive Supervisor Behaviors Enhance Employees' Work-Family Enrichment? Thriving at Work as Mediator and Intrinsic Motivation as Moderator. [PDF]
Psychol Res Behav Manag, 2022 Shen C, Liu R, Yang J, Hu S, He P.
europepmc +1 more source
, 2017 We applied the resource–gain–development perspective to test a theoretical model in which family-supportive supervisor behaviors (FSSB) were expected to predict work engagement through the mediator of bidirectional work–family enrichment (work–family ...
Erhua Zhou, Guoxia Qing
core +1 more source