Results 51 to 60 of about 370,298 (295)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Effects of work-to-family enrichment on psychological distress and family satisfaction: A dyadic analysis in dual-earner parents

, 2022
Resources that individuals acquire at work can have significant effects on their own well-being and family satisfaction, and on those of their closest family relations.
Miranda Zapata, Edgardo, Schnettler, Berta, Garcia, Romina, Orellana, Ligia   +3 more
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Work-family balance measures in companies and employees’ work satisfaction: the effect of work-family enrichment [PDF]

ESIC MARKET Economic and Business Journal, 2017
This paper analyses the relationship between a group of different practices of work-family balance and the employees’ job satisfaction, as well as the relationship between job satisfaction and employee’s organizational commitment. We differentiate this relationship according to the level of work-family (W-F) enrichment and family-work (F-W) enrichment,
Pérez Pérez, Manuela, Vela Jiménez, María José, Abella Garcés, Silvia, Martínez Sánchez, Ángel   +3 more
openaire   +3 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Good marriage at home, creativity at work: Family–work enrichment effect on workplace creativity

, 2017
To advance the understanding of socio-relational sources of employee creativity, we investigate the effect of a good marriage on workplace creativity.
Tang, Y, Xu Huang, Yongli Wang, Wang, Y, Huang, X, Yipeng Tang   +5 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

The antecedents and outcomes of work-family enrichment amongst female workers

SA Journal of Industrial Psychology, 2014
Orientation: Women are involved in both a work and a family domain. Work-family enrichment is a concept that describes how these domains can enrich each other through the transfer of resources from one domain to the other. Research purpose: The objective
Esandre Marais, Marissa de Klerk, Jan Alewyn Nel, Leon de Beer   +3 more
doaj   +1 more source