Results 221 to 230 of about 25,491,123 (302)

Assessing social determinants of health needs in newly diagnosed gynecologic oncology patients and their relationship with social support and stress levels. [PDF]

Gynecol Oncol Rep
Karvandi R, Jorgensen J, Pella JE.
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Primary healthcare providers' strategies of handling patients presenting with potential cancer symptoms following the introduction of standardized cancer patient pathways in Sweden. [PDF]

BMC Prim Care
Fjällström P, Coe AB, Lilja M, Hajdarevic S.   +3 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Biological Mechanisms Underlying the Adverse Health Consequences of Human Circadian Misalignment from Night Shift Work. [PDF]

Curr Sleep Med Rep
Lundholm KR, Satterfield BC, Banks S, Liu PY, Kombala CJ, Hurtado-Alvarado G, Greer AJ, Muck RA, Layton MA, Du D, Gaddameedhi S, Van Dongen HPA.   +11 more
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Association of the metabolic signature of sleep patterns with breast cancer risk: a prospective cohort study. [PDF]

Front Endocrinol (Lausanne)
Yang Q, Ai F, Zhao Y, Wang Z, Bi Z, Ma R, Xu D.   +6 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Polymer-Based Additive Manufacturing in Cervical Cancer Management: A Review. [PDF]

Polymers (Basel)
Wang X, Lin N, Cao Y, Vishwakarma J, Liu X, Ren C.   +5 more
europepmc   +1 more source