Results 91 to 100 of about 22,350,899 (207)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Determination of Nurses' Work-Related Stress and Job Satisfaction Levels
Sağlık ve Hemşirelik Yönetimi DergisiAim: This study aimed to determine the work-related stress and job satisfaction levels of nurses working in a university hospital and to examine the factors influencing these variables. Method: The study employed a descriptive and correlational research
Kamil Bucaklı, Alime Selçuk Tosun
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Work-related stress in the Italian banking population and its association with recovery experience [PDF]
, 2019 Objectives Over the past decade, there has been a markedly growing interest in issues involving work-related stress in Europe. In Italy, according to Eurofound, research has demonstrated high levels of stress in the banking sector.
Arcangeli, Giulio +12 more
core +2 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
INSURANCE INTERMEDIARIES’ WORK-RELATED STRESS: CONNECTIONS WITH LABOUR PRODUCTIVITY
Ekonomika, 2014 . The article deals with work-related stress, the reasons for its occurrence, consequences, and ways how to manage stress in the Lithuanian “X” life insurance company.
Violeta Raimonda Kulvinskienė +1 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Stress, psychophysiological indices and work related applications [PDF]
, 2022 openLo stress è una condizione intrinseca alla vita dell'uomo, se permane comporta delle conseguenze alla salute. La ricerca oggi utilizza la psicofisiologia per la misurazione oggettiva dello stress e studia i suoi metodi di rilevazione in ambito ...
REGGIANI, ALICE
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
MedicinaBackground and Objectives: Tinnitus is a common symptom in otolaryngologic practice. Although its pathophysiology is multifactorial and remains mostly unclear, it can be correlated to stress and psychological comorbidities.
Berit Hackenberg +17 more
doaj +1 more source