Results 81 to 90 of about 22,350,899 (207)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

STRESS AT THE WORK IN ROMANIAN BANKING SISTEM [PDF]

In a period when the banks are struggling to survive we can realize that stress management becomes a problem. Stress at work can bring real business problems, management and labor productivity can be seriously affected and the level of motivation and ...
Breje Cristina
core  

Can We Improve the Assessment of Work Characteristics by Completely Contextualizing Items?

Scandinavian Journal of Work and Organizational Psychology
Employee surveys are a cost-effective way to assess work-related stress, but their generic formulation often allows for broad interpretation. Research from personality assessment suggests that contextualizing survey items may enhance reliability and ...
Berit Greulich, Cornelius J. König, Carla V. Meixensberger   +2 more
doaj   +1 more source

Work-related stress and musculoskeletal complaints of orchestra musicians

Revista Dor, 2014
BACKGROUND AND OBJECTIVES:Professional musicians are commonly affected by musculoskeletal discomfort. Understanding the association of such affections with psychic health may contribute to promote the health of such professionals. So, this study aimed at
Érico Felden Pereira, Fausto Kothe, Fernanda Tolentino de Souza Bleyer, Clarissa Stefani Teixeira   +3 more
doaj   +2 more sources

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Job Anxiety, Work-Related Psychological Illness and Workplace Performance [PDF]

This paper uses matched employee-employer data from the British Workplace Employment Relations Survey (WERS) 2004 to examine the determinants of employee job anxiety and work-related psychological illness.
Jones, Melanie K., Latreille, Paul L., Sloane, Peter J.   +2 more
core  

Occupational stress among nurses in the Ashanti Region of Ghana: a comparative cross-sectional study of government and private hospitals

BMC Nursing
Background Occupational stress, which negatively affects nurses’ health, job satisfaction, and quality of patient care, is a major challenge in nursing.
Benjamin Antwi Boasiako, Joana Apenkwa, Denis Dekugmen Yar, Prince Kwabena Achoo, Crispen Kandatam   +4 more
doaj   +1 more source

Bullying and Work-Related Stress in the Irish Workplace

Societies, 2019
Work-related stress is increasing in prevalence, with important consequences for employees, employers, the economy, and wider society. While previous research has identified a link between work-related stress and bullying, gaps remain in our ...
John Cullinan, Margaret Hodgins, Victoria Hogan, Michael McDermott, Sharon Walsh   +4 more
doaj   +1 more source