Results 91 to 100 of about 40,520,256 (406)
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield+3 more
wiley +1 more source
Work of the Department of Terrestrial Magnetism of the Carnegie Institution of Washington for 1905 [PDF]
L. A. Bauer
openalex +1 more source
Besov regularity for operator equations on patchwise smooth manifolds [PDF]
We study regularity properties of solutions to operator equations on patchwise smooth manifolds $\partial\Omega$ such as, e.g., boundaries of polyhedral domains $\Omega \subset \mathbb{R}^3$. Using suitable biorthogonal wavelet bases $\Psi$, we introduce
Dahlke, Stephan, Weimar, Markus
core
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker+8 more
wiley +1 more source
Magnetic Work of the British National Antarctic Expedition of 1901-4 [PDF]
L. A. Bauer
openalex +1 more source
Forced Labour in Latin America [PDF]
A fact sheet on forced labor in the Latin American region, inclusive of statistics and an outline of the ILO’s actions against ...
Declaration on Fundamental Principles and Rights at Work+1 more
core +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan+2 more
wiley +1 more source
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi+5 more
wiley +1 more source
In the course of human intelligence development, there is an increase in the volume of intellectual property objects and, accordingly, the need to protect these relations within the framework of the law.
Svyatoslav O. Khatsko / Святослав О. Хатько
doaj +1 more source
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile+8 more
wiley +1 more source