Results 131 to 140 of about 3,783,867 (355)
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
While research is mainly focused on the role of gender and biological/chronological age in the relationship between Work Ability Index and Effort/Reward Imbalance, this study addresses the association between work-related stress and work ability, taking
P. Campanini +6 more
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Este estudo avaliou a capacidade para o trabalho de trabalhadoras brasileiras por grupo de idade e ocupação e analisou as ausências por doença registradas durante um ano.
Maria Silvia Monteiro +2 more
doaj +1 more source
Effort Reward Imbalance and Work Ability among nurses and call-center operators
The aim of the study is to investigate the relationship between effort/reward imbalance and work ability in the nursing and call-center sectors. A selfreported questionnaire was completed by 1,113 nurses and 1,106 call-center operators.
G. Castellini +5 more
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Extensive Reading and the Writing Ability of EFL Learners: the Effect of Group Work
openalex +1 more source

