Results 141 to 150 of about 9,961,088 (302)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Study the relation between Work Ability Index and Life Style in Mechanics of Thermal power plant

open access: yesMuhandisī-i bihdāsht-i ḥirfah/ī, 2016
Introduction: Maintenance of work ability and continuous effort to improve reduced work ability of employees is a major concern for managers. This study aimed to determine the level of work ability index and relation with life style in mechanics of ...
Keivan Saedpanah   +5 more
doaj  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

A study on factors affecting on work ability among farmers in the Ashtian city

open access: yesSalāmat-i kār-i Īrān, 2017
Background and aims: Monitoring workerschr('39') work ability, planning to maintain and improve the work ability, and identifying and controlling its related risk factors are of the most important issues in the field of occupational health. The object of
Akbar Rostam Abadi, Adel Mazloumi
doaj  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Fostering Work Ability Among Menopausal Women. Does Any Work-Related Psychosocial Factor Help?

open access: yesInternational Journal of Women's Health, 2020
Sara Viotti, Gloria Guidetti, Daniela Converso, Ilaria Sottimano Department of Psychology, University of Turin, Turin, ItalyCorrespondence: Gloria Guidetti Via Verdi 10, Turin 10124, ItalyEmail gloria.guidetti@gmail.comIntroduction: Due to the aging ...
Viotti S   +3 more
doaj  

A note on multitask learning and the reorganization of work [PDF]

open access: yes
In this note, we investigate the necessary condition for a firm to be able to move from Tayloristic to ohlistic organization of work, whatever the economic conditions and the incentives to do it: that workers have the ability to allocate their work-time ...
Xavier Pautrel
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Increasing evidence of physical loads as risk factors for specific shoulder disorders

open access: yesScandinavian Journal of Work, Environment & Health, 2010
Eira Viikari-Juntura
doaj   +1 more source

Analytical evaluation of work ability index and its determining factors among workers of a car manufacturing industry

open access: yesSalāmat-i kār-i Īrān, 2012
Background and aims : The ability of work is the basis of well-being for all of us. Many factors affect the work ability such as work and work condition, work organization and human resource. The aim of this study was to assess the work ability among car
M Eyvazlou   +3 more
doaj  

Home - About - Disclaimer - Privacy