Results 81 to 90 of about 9,913,320 (301)

Assessment of the Work Ability Index among Iranian Employees: A Systematic Review

تحقیقات سلامت در جامعه, 2022
Introduction and purpose: The ability to work is one of the important factors in predicting the working conditions, well-being, and health status of employees.
Haji Omid kalteh, Siavash Etemadinejad, Elahe Amouzadeh, Ali Tajpoor, Solaleh Ramezani   +4 more
doaj  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Employee Satisfaction With Working Space and Its Association With Well-Being—A Cross-Sectional Study in a Multi-Space Office

Frontiers in Public Health, 2019
Introduction: Different kinds of shared and activity-based offices are common today and employees' experiences, perceived health, well-being, satisfaction, and productivity have been studied in different types and sizes of environments.Objectives: In ...
Sirpa Lusa, Sari Mirjami Käpykangas, Heli Ansio, Pia Houni, Jukka Uitti, Jukka Uitti   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Executive dysfunction in cerebral small vessel disease: A subdomain analysis with conventional and experimental assessment methods

Cerebral Circulation - Cognition and Behavior
Introduction: Executive functions and processing speed have been regarded as core cognitive domains affected in cerebral small vessel disease (SVD). Executive functions, as an umbrella concept, consist of a variety of different subcomponents, yet in ...
Hanna Jokinen, Hanna M. Laakso, Anne Arola, Teemu Paajanen, Jussi Virkkala, Teppo Särkämö, Tommi Makkonen, Heidi Heinonen, Johanna Pitkänen, Antti Korvenoja, Susanna Melkas   +10 more
doaj   +1 more source

Correlates of employment status in individuals with asthma: a cross-sectional survey

Journal of Occupational Medicine and Toxicology, 2017
Background This study aims to elucidate factors that among adults with asthma are associated with working full-time. Methods This cross-sectional survey of 2613 working-age adults with asthma included questions on asthma history, symptoms and use of ...
Saara Taponen, Lauri Lehtimäki, Kirsi Karvala, Ritva Luukkonen, Jukka Uitti   +4 more
doaj   +1 more source

The managerial relevance of maintenance of work ability: A Finnish perspective [PDF]

, 2004
Finland has pursued a law-based work ability policy for more than a decade. Many studies indicate that it has been very successful from a health point of view.
Hussi, Tomi
core  

From Work Ability Research to Implementation [PDF]

International Journal of Environmental Research and Public Health, 2019
Work ability research started in Finland in the 1990s due to the challenges of work force aging. The employment rates of older workers (55+) were below 40% and early retirement and work disability rates were rather common in many European countries. The work ability concept and methods were developed and broad international research activities started ...
openaire   +2 more sources