Results 131 to 140 of about 24,768,390 (357)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
PENGARUH MOTIVASI DAN LINGKUNGAN KERJA TERHADAP KINERJA KARYAWAN PADA PT BANK RAKYAT INDONESIA TBK LAMONGAN [PDF]
This research aims to determine and analyze the influence of work motivation and work environment on the performance of PT Bank Rakyat Indonesia Tbk employees. The population in this study was 31 employees.
Quddus, Muhammad Malikul
core
, 2016 The Theme of the 5th Annual Conference on Social Work in the Global Environment was: Environmental and Ecological Justice, Human RIghts, and Socio-Economic Justice: Local and Global ...
Department of Social Work, Kutztown University of Pennsylvania
core +1 more source
WeCanWork study: well-being of male cancer survivors working physically demanding jobs
BMC Public HealthBackground Male cancer survivors performing physically demanding work have received less attention in the scientific literature compared to other groups.
Natalie V. Schwatka +8 more
doaj +1 more source
Occupational exposure to particles and incidence of stroke
Scandinavian Journal of Work, Environment & Health, 2013 OBJECTIVES: This paper aims to investigate the relation between occupational exposure to particles, particle size, and the incidence of ischemic and hemorrhagic stroke.
Bengt Sjögren +8 more
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Factors Associated with Preferences Regarding Selected Forms of Variable Pay: A Replication and Extension [PDF]
, 2013 This study investigates the relationships among being paid via different variable pay systems, perceptions regarding selected work environment characteristics, and preferences regarding selected variable pay plans.
Inderrieden, Edward +2 more
core +1 more source