Results 141 to 150 of about 243,937 (306)

Critical Resolved Shear Stress and Work Hardening Determination in HCP Metals: Application to Zr Single Crystals

Metals
Obtaining precise parameters of deformation modes remains a significant challenge in materials science research. Critical resolved shear stresses (CRSS) and work hardening, particularly in hexagonal metals, are crucial parameters for constitutive laws in
Jean-Sébastien Lecomte, Jérôme Crépin, Pierre Barberis   +2 more
doaj   +1 more source

Work hardening behavior of hot-rolled metastable Fe₅₀Co₂₅Ni₁₀Al₅Ti₅Mo₅ medium-entropy alloy: in situ neutron diffraction analysis. [PDF]

Sci Technol Adv Mater, 2022
Kwon H, Harjo S, Kawasaki T, Gong W, Jeong SG, Kim ES, Sathiyamoorthi P, Kato H, Kim HS.   +8 more
europepmc   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Work Hardening of Heat-Treated AlSi10Mg Alloy Manufactured by Selective Laser Melting: Effects of Layer Thickness and Hatch Spacing. [PDF]

Materials (Basel), 2021
Ghio E, Cerri E.
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Two new mathematical models to predict the flow stress at hot deformation

, 2014
Based on both linear and non-linear estimations of work hardening rate versus strain curves, two mathematical models have been developed to predict the flow curves under hot working conditions up to the peak.
Solhjoo, Soheil
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

A theory of viscoplasticity accounting for internal damage [PDF]

A constitutive theory for use in structural and durability analyses of high temperature isotropic alloys is presented. Constitutive equations based upon a potential function are determined from conditions of stability and physical considerations.
Freed, A. D., Robinson, D. N.
core   +1 more source