Results 121 to 130 of about 13,124,768 (302)

A Data-Driven Approach for Studying the Influence of Carbides on Work Hardening of Steel. [PDF]

open access: yesMaterials (Basel), 2022
Vittorietti M   +4 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Effects of Work-Hardening Exponent and Strain-Rate Hardening Exponent on the Determination of Friction Factor

open access: yes, 1992
The ring compression test has been widely employed as an experimental means to determine the friction factor. The calibration curves are obtained by the rigid-plastic finite element analysis for various work-hardening exponent and strain-rate hardening ...
양동열, 박치용
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Hardening of an Al-Cu-Mg alloy containing type I and II S phase precipitates

open access: yes, 2010
The effect of different thermo-mechanical treatments on the hardness of the 2024 (Al-Cu-Mg) alloy was studied. Artificial ageing was conducted through heating at a constant rate to specific temperatures followed by rapid cooling.
Starink, M.J., Wang, S.C., Parel, T.S.
core   +1 more source

Revisiting gouging abrasion test for jaw crushers

open access: yesREM: International Engineering Journal
The use of a gouging abrasion test to evaluate the wear of jaw crushers is revised in terms of its procedures, considering the effects of the most significant variables, such as the minimum amount of crushed material and the minimum opening between the ...
Giuseppe Pintaude, Nilson Mar Bartalini
doaj   +1 more source

Novel Permanent Magnetic Surface Work Hardening Process for 60/40 Brass. [PDF]

open access: yesMaterials (Basel), 2021
Alaskari AM   +4 more
europepmc   +1 more source

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