Results 61 to 70 of about 242,010 (302)
Metals, 2019 Tensile behavior and plastic deformation mechanisms of Fe-22.8Mn-8.48Al-0.86C low-density steel were studied in this thesis. After solution treatment 1100 °C for 1 h; the steels obtained an excellent combination in mechanical properties; with ...
Jingyu Pang +5 more
doaj +1 more source
Numerical modeling of strain rate hardening effects on viscoplastic behavior of metallic materials [PDF]
, 2017 The main goal of the present work is to provide a finite strain elasticviscoplastic framework to numerically account for strain, strain rate hardening, and viscous effects in cold deformation of metallic materials. The aim is to provide a simple and robust
Dos Santos, Tiago +3 more
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Compaction Behavior of Isomalt after Roll Compaction
Pharmaceutics, 2012 The suitability of the new isomalt grade galenIQ™ 801 for dry granulation and following tableting is evaluated in this study. Isomalt alone, as well as a blend of equal parts with dibasic calcium phosphate, is roll compacted and tableted ...
Peter Kleinebudde +2 more
doaj +1 more source
A viscoplasticity model with an enhanced control of the yield surface distortion
, 2012 A new model of metal viscoplasticity, which takes combined isotropic, kinematic, and distortional hardening into account, is presented. The basic modeling assumptions are illustrated using a new two-dimensional rheological analogy.
Ihlemann, J., Shutov, A. V.
core +1 more source
Role of Age Hardening Heat Treatment on the Hardness Values of 93.95 Al-5 Zn-1.05 Sn/5 Al2o3- Sio2 Particulate Composite [PDF]
, 2014 - The effect of age hardening heat treatment on the hardness values of 93.95Al-5Zn-1.05Sn/5Al2O3-SiO2 particulate composite has been studied. The data used for the work was generated at the National Metallurgical Development Centre, Jos Foundry shop ...
Ihom, A. P. (Aondona)
core +3 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Optimizing dual energy cone beam CT protocols for preclinical imaging and radiation research [PDF]
, 2017 Objective: The aim of this work was to investigate whether quantitative dual-energy CT (DECT) imaging is feasible for small animal irradiators with an integrated cone-beam CT (CBCT) system.
Almeida, Isabel P +7 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source