Results 81 to 90 of about 243,937 (306)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Deformation Behavior of High-Mn TWIP Steels Processed by Warm-to-Hot Working
Metals, 2018 The deformation behavior of 18%Mn TWIP steels (upon tensile tests) subjected to warm-to-hot rolling was analyzed in terms of Ludwigson-type relationship, i.e., σ = K1·εn1 + exp(K2 − n2·ε). Parameters of Ki and ni
Vladimir Torganchuk +3 more
doaj +1 more source
, 2005 A Phenomenological Mesoscopic Field Dislocation Mechanics (PMFDM) model is developed, extending continuum plasticity theory for studying initial-boundary value problems of small-scale plasticity.
Acharya, Amit, Roy, Anish
core +1 more source
Role of Age Hardening Heat Treatment on the Hardness Values of 93.95 Al-5 Zn-1.05 Sn/5 Al2o3- Sio2 Particulate Composite [PDF]
, 2014 - The effect of age hardening heat treatment on the hardness values of 93.95Al-5Zn-1.05Sn/5Al2O3-SiO2 particulate composite has been studied. The data used for the work was generated at the National Metallurgical Development Centre, Jos Foundry shop ...
Ihom, A. P. (Aondona)
core +3 more sources
AAOHN Journal, 1990 Work hardening is a highly specialized rehabilitation program that spans the transition from traditional rehabilitation therapies to return to work by simulating workplace activities and surroundings in a monitored environment. The goal is to create an environment in which returning workers can rebuild psychological self-confidence and physical ...
openaire +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Work-Hardening in Three-Dimensional Slip-Line Fields
Engineering Transactions, 1996 A slip-line field theory that includes rotational continuity, published in an earlier article and shown therein to lead to Hill's equiangular net, is extended to include work-hardening.
R.L. Bish
doaj
Metals, 2018 The objective of the present study is to analyze the microstructure and mechanical properties of a twinning-induced plasticity (TWIP) steel at different temperatures.
Flavio De Barbieri +4 more
doaj +1 more source