Results 71 to 80 of about 13,124,768 (302)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Precipitation, strength and work hardening of age hardened aluminium alloys [PDF]

open access: yes, 2015
The strength and work hardening of age hardened AA6063 and AA6082 alloys have been investigated in terms of a detailed characterization of precipitate and dislocation structures obtained by TEM and SEM.
Marthinsen, Knut   +3 more
core   +2 more sources

Study on the Machined Surface Quality in High Speed Turning High Strength Steel under Cryogenic Minimum Quantity Lubrication

open access: yesJournal of Harbin University of Science and Technology, 2019
Based on process parameter optimization results, the influence laws and reasons of different cutting environments and cutting parameters(cutting speed, feed), process parameter (jet temperature, cutting oil amount) under cryogenic minimum quantity ...
ZHANG Huiping   +3 more
doaj   +1 more source

A Constitutive Model for Yield Strength and Work Hardening Behaviour of Aluminium Alloys during Artificial Ageing

open access: yesMetals, 2020
In this study, a unified constitutive model has been developed for both yield strength and work hardening behaviour prediction of aluminium alloys with different types of precipitates during and after artificial ageing.
Kang Ji   +7 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Surface hardening effect on the fatigue behavior of isotropic beam

open access: yes, 2022
an experimental study of the impact of surface hardening on the high-cycle fatigue behavior of an isotropic beam.The beams are made from low carbon steel.The experimental work included mechanical tests, surface heat treatment, fatigue tests, and ...
Sajjad H, Nasser, Qasim H. Bader
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Work hardening behavior in aluminum alloy 2090 [PDF]

open access: yes, 1993
An investigation into the work hardening behavior of an aluminum alloy 2090-T81 Al-3.05Cu-2.16Li-0.12Zr at various test temperatures, heat treatment conditions and microstructures was conducted.
Tseng, C.
core  

Work hardening in Fe-Al alloys

open access: yes, 2013
Work hardening in polycrystalline Fe-Al alloys has been examined for alloys containing from nearly no Al up to about 40 at.% Al. A sharp maximum in work hardening is seen for alloys containing 26-30% Al.
Morris, David G.   +2 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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