Results 171 to 180 of about 1,677,634 (260)

Advancing Equity, Diversity, Inclusion, and Accessibility in a Patient-Oriented Kidney Research Network: A Can-SOLVE CKD Program Report. [PDF]

Can J Kidney Health Dis
Turino Miranda K, Jones J, Talson MD, Scholey J, Wysocki J, Elliott MJ, Pokiak L, Torrejon M, Harris H, Allu S.   +9 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

A social cognitive perspective on teacher technology self-efficacy, inclusion, and student aspirations. [PDF]

BMC Psychol
Lei H, Na F, Lu L, Soomro HJ, Zaigham GHK.   +4 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Culturally and regionally relevant physical activity for public health promotion in a global context: nature of the evidence and definition development from a narrative review. [PDF]

BMJ Public Health
Sentell TL, Pirkle CM, Grout L, Ylli A, Heil DP, Schmid SM, Finn J, Câmara SMA, Yokooji E, Look MA.   +9 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Assistive technologies in employment and entrepreneurship: Graduates with sensory disabilities. [PDF]

Afr J Disabil
Xashimba S, de Beer M.
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Evaluating the Use of a Commercial Bacterial Biomass as a Bioactive Component of Pacific White Shrimp <i>Litopenaeus vannamei</i> Feeds. [PDF]

Aquac Nutr
Tabbara M, Araujo A, Nazeer S, Peixoto S, Smullen R, Briggs M, Davis DA.   +6 more
europepmc   +1 more source