Results 191 to 200 of about 1,770,568 (261)

Inclusion of pregnant and lactating women in TB treatment and vaccine trials. [PDF]

IJTLD Open
Meehan SA, Hesseling AC, Viljoen L, Cranmer LM, Verkuijl S, Viney K, Maktabi M, Isaacs M, Hirsch-Moverman Y.   +8 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Iterative Development of an AI-Assisted Data Extraction Tool for Literature Synthesis in Oncology. [PDF]

Cureus
Liu A, Alfadli F, Wong P.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

AI-enabled integrated employment ecosystem for socially vulnerable groups: a multiple case study and design-research approach. [PDF]

Front Sociol
Roh BG.
europepmc   +1 more source

TRAINING FOR WORK IN INCLUSIVE EDUCATION

Sovremennye issledovaniya sotsialnykh problem, 2014
openaire   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Disability, Chronic Illness, and Belonging in Medical Training: A Scoping Review of Perceptions, Lived Experiences, and Inclusion. [PDF]

Adv Med Educ Pract
Truong JB, Knickerbocker AC, Stanley-Kime K.   +2 more
europepmc   +1 more source

Evaluation of the jejunal microbiota and microbial markers in laying hens fed diets with black soldier fly larval fat as a partial or total replacement for soybean oil. [PDF]

Poult Sci
Kierończyk B, Drażbo A, Juśkiewicz J, Kozłowski K, Szymkowiak P, Ciesielska L, Praska D, Aslam MR, Rawski M, Józefiak D.   +9 more
europepmc   +1 more source