Results 231 to 240 of about 6,290,411 (300)

An Unusual Presentation of a Left Extra-acetabular Trochanteric Bursa Abscess. [PDF]

Cureus
Ewart MJ, Mohammad S, Erickson D, Platis B, Certeza J, Powell J, Khan F, Karnkowska B, Marrufo I, Fisher CL.   +9 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Targeted literature review of concepts related to women's experiences and perceptions of vasomotor symptoms associated with menopause. [PDF]

Menopause
Bin Ng D, Burgess SM, Tsai CC, Henze M, Chladek M, Hadi FA.   +5 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Singularity in nonlinear systems: differential inclusion model for the standard and transformed fractional pantograph equation. [PDF]

Sci Rep
Mobayen S, Ghaderi M, Shabibi M, Parvaneh Masiha H, Rezapour S.   +4 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Correction: Promoting resilience and sexual and reproductive health among adolescent migrants: a comprehensive approach. [PDF]

Front Psychiatry
Georgalis A, Thomson R.
europepmc   +1 more source

MetaCAM as an ensemble-based class activation mapping framework improves model explainability. [PDF]

Sci Rep
Dick K, Kaczmarek E, Miguel OX, Bowie AC, Ducharme R, Dingwall-Harvey ALJ, Hawken S, Armour CM, Walker MC.   +8 more
europepmc   +1 more source

Centring Social Justice in Nursing Educational Resources: Equity, Diversity, and Inclusion. [PDF]

Can J Nurs Res
Lapum JL, St-Amant O, Hughes M, Garmaise-Yee J.   +3 more
europepmc   +1 more source

Balance the scale: inclusive learning environment and inclusive working environment

Advances in Physiology Education
openaire   +2 more sources