Results 231 to 240 of about 6,272,871 (300)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Inclusive Leadership and Intent to Stay in a Midwestern US Nonprofit Faith-Based Hospital - A Cross-Sectional Study of Nursing Staff. [PDF]

J Healthc Leadersh
Swen RW, Brown DW, Luallen M.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Role of organizational network analyses to advance workforce inclusion and belonging: a scoping literature review. [PDF]

Front Psychol
Decker-Tonnesen PL, Chesak SS, Walker LE, Kohler K, Phelan S, Gunnels MS, Saliba KL, Bhagra A.   +7 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Discrimination, school inclusion, and quality of life in adolescence: a mediation analysis. [PDF]

Front Psychol
Ayuso-Lanchares A, González-Sangino C, Rodríguez-Medina J.   +2 more
europepmc   +1 more source

Friendship networks predict girls' STEM fit and interest through subjective belonging. [PDF]

Group Process Intergroup Relat
Cyr EN, Steele JR, Schmader T, Robinson K, Wright SC, Spencer SJ, Bergsieker HB.   +6 more
europepmc   +1 more source

Retired para athletes hold limited leadership roles in Canadian national sport federations. [PDF]

Front Sports Act Living
Stevenson C, Mortenson WB, Peng TH, Miniato A, Walker-Young E, Willsie D, Gruenig S, Bundon A, Lawson S, Landry M, Pollock CL.   +10 more
europepmc   +1 more source