Results 51 to 60 of about 1,809,942 (310)

Work solutions: improving cultural diversity and inclusion in the workplace [PDF]

open access: yes, 2014
Victoria would do well to make the most of its human resources and embrace newcomers who want to work no matter where they have been educated and gained their skills and experience.
Ethnic Communities' Council of Victoria
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Moments of inclusion and exclusion: pupils negotiating classroom contexts [PDF]

open access: yes, 2003
This paper uses evidence form a small-scale study of two English primary classrooms to examine school inclusion in its political contexts. We argue that 'inclusion' and 'exclusion' are complex process, enacted moment-by-moment by pupils and teachers. Our
Nind, M.   +8 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Virtual inclusion in the City

open access: yes, 2020
On March 16th 2020 the UK Prime Minister Boris Johnson started giving the nation daily updates urging its citizens to work from home as part of the COVID-19 response.
Lordan, Grace
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Place-train i møte med aktiveringspolitikk og tverrsektoriell samhandling: En litteraturbasert drøfting av norsk praksis

open access: yesSøkelys på Arbeidslivet
Et utviklingstrekk i arbeidsmarkedspolitikken både i Norge og internasjonalt er økt bruk av inkluderingsinnsatser som foregår på ordinære arbeidsplasser (place-train) og mindre bruk av tiltak som skal forberede den enkelte på å møte arbeidslivets krav ...
Line Fossum Skogstad
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Solid-state NMR studies of inclusion compounds [PDF]

open access: yes, 1997
The work contained within this thesis is a study of inclusion compounds using solid-state NMR. Such compounds typically exhibit static and/or dynamic disorder, which precludes the use of diffraction-based techniques to obtain detailed structural ...
Nordon, Alison
core  

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