Results 21 to 30 of about 4,196,836 (307)
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
İNSANA YAKIŞIR İŞ VE ÇALIŞAN YOKSULLAR: İŞGÜCÜ PİYASASI ÇERÇEVESİNDE BİR DEĞERLENDİRME
Ekonomi Maliye İşletme Dergisi, 2021 The concept of decent work aims to offer individuals a better life. It is briefly defined as the work in which the conditions of freedom, equality, security, and dignity are ensured; and it emphasized that human dignity and productivity should be ...
Gülşen ÇETİN AYDIN
doaj +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Attitudes Towards Work And The Market Economy In Bulgaria [PDF]
, 1992 [Excerpt] As in the reports on Poland (Ruiz Quintanilla 1992a) and Hungary (Ruiz Quintanilla 1992b), this summary will center on how life has changed in Bulgaria as evaluated by the Bulgarian people.
Ruiz-Quintanilla, S. Antonio
core +1 more source
Dignity and work: global market and self-sustenance
The Journal for Transdisciplinary Research in Southern Africa, 2007 It is argued here that market fundamentalistic theories ignore the issue of human agency in work, and the different types of work, because – focussing on the market mechanism, supply, demand, and price - they have lost track of that which economic ...
J.J. (Ponti) Venter
doaj +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Attitudes Towards Work and the Market Economy in Poland [PDF]
, 1992 [Excerpt] The results of the June, 1989 elections demonstrated the willingness of a majority of the Polish people to initiate the change from a one-party regime to political pluralism.
Ruiz-Quintanilla, S. Antonio
core +1 more source
Welfare conditionality, inequality and unemployed people with alternative values [PDF]
, 2010 Labour and Conservatives’ claims that welfare conditionality is ‘fair’ rely upon an empirically unsupported assumption that almost-equal opportunities can exist alongside starkly unequal outcomes.
Andrew Dunn +39 more
core +1 more source
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Attitudes Towards Work and the Market Economy in Hungary [PDF]
, 1992 [Excerpt] A common approach in describing countries in Eastern and Central Europe is to focus on similarities among them currently and in their past but to neglect differences.
Ruiz-Quintanilla, S. Antonio
core +1 more source