Results 51 to 60 of about 3,097,249 (298)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Human resources development in Salatiga city education department (analysis of work discipline and work motivation on performance mediated by education and job training of employees)

JPPI (Jurnal Penelitian Pendidikan Indonesia), 2023
The purpose of this research is to analyze and explain the effect of work discipline, work motivation, education and training on performance. analyze and explain whether education and training mediate work discipline and motivation on the performance of ...
Samtono Samtono, Tri Maryani
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Motivasi Kerja Pegawai Di Kantor Keyahbandaran Utama Makassar

Jurnal Ilmiah Manajemen dan Bisnis, 2017
This study aims to determine the motivation of employees at the Office Kesyahbandaran Utama Makassar. The type of research is descriptive, with population of all employees at Kesyahbandaran Utama Makassar Office amounting to 265 people / employees ...
Muh Nasrullah, Rudi Salam, Dwi Pratiwi, Risma Niswaty   +3 more
doaj   +1 more source

The Effect of Work Motivation Factors on Job Satisfaction in XY Company [PDF]

, 2015
The reason behind this research is because XY company faces low productivity and low employee motivation problems. The purpose of this research is to give solutions towards XY's problem. Respondent of this research is employee of production division of
Suhartono, S. (Suhartono)
core  

Predicting Students’ Physical Activity and Health-Related Well-Being: A Prospective Cross-Domain Investigation of Motivation Across School Physical Education and Exercise Settings \ud [PDF]

, 2012
A three-wave prospective design was used to assess a model of motivation guided by self-determination theory (Ryan & Deci, 2008) spanning the contexts of school physical education (PE) and exercise.
Gillison, Fiona B, Ntoumanis, Nikos, Standage, Martyn, Treasure, Darren C   +3 more
core   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

PENGARUH UPAH TERHADAP MOTIVASI KERJA KARYAWAN HOME INDUSTRY GAMELAN MITRA JAYA MAGETAN

EQUILIBRIUM: Jurnal Ilmiah Ekonomi dan Pembelajarannya, 2016
This study aims to determine the remuneration to the home industry Gamelan Mitra Jaya Magetan, to know the motivation of employees working at home industry Gamelan Mitra Jaya Magetan as well as to determine whether or not the influence of remuneration on
Nisa Nur Hidayah
doaj   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

INFLUENCE OF MOTIVATION ON WORK ACTIVITY [PDF]

Sport Mont, 2008
According to empirical and theoretic explorations human behavior, and work activity in roots are motivated from a different needs in a function to achieve personal interests and goals.
Šemsudin Plojović
doaj