Results 31 to 40 of about 1,568,884 (267)

Testing Longitudinal Measurement Invariance of the Dutch PSS-10, MBI-ES, and PANAS in a Bimonthly 6-Month Panel

Psychologica Belgica
Monitoring teacher well-being over time is essential in both research and practice to understand changes, evaluate interventions, and support occupational health.
Justine Van de Velde, Bert Weijters, Katia Levecque   +2 more
doaj   +1 more source

Evaluation of the quality of working life and its effective factors in employed nurses of Tehran University of Medical Sciences Hospitals

Journal of Education and Health Promotion, 2021
BACKGROUND: Quality of working life (QWL) refers to aspects of life quality, which are related to work settings. This study was designed to evaluate the QWL and its effective factors among nurses of Tehran University of Medical Sciences Hospitals ...
Farahnaz Khajehnasiri, Abbas Rahimi Foroushani, Bita Forati Kashani, Negin Kassiri   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Identifying patient subgroups in MASLD and MASH-associated fibrosis: molecular profiles and implications for drug development

Scientific Reports
The incidence of MASLD and MASH-associated fibrosis is rapidly increasing worldwide. Drug therapy is hampered by large patient variability and partial representation of human MASH fibrosis in preclinical models.
Manuel A. González Hernández, Lars Verschuren, Martien P.M. Caspers, Martine C. Morrison, Jennifer Venhorst, Jelle T. van den Berg, Beatrice Coornaert, Roeland Hanemaaijer, Gerard J. P. van Westen   +8 more
doaj   +1 more source

The Social Responsibility Of NGOs For Achieving Social and Economic Empowerment Of Orphan Families [PDF]

مجلة مستقبل العلوم الإجتماعیة
The present study aimed to examine the role of the social responsibility of NGOs in achieving social and economic empowerment for orphan families. The significance of the study lies in its linkage between the responsibilities of community organizations ...
Mohamed Ata Ahmed Abdel Aziz
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Les compétences pour négocier l’organisation du travail : le cas d’un projet industriel d’automatisation

Activités, 2018
Our intervention research is based on a project to automate a production sector of a steel company coupled with downsizing. We sought to understand how, within this framework, the working group, made up of supervisors, operators and an ergonomist ...
Agathe Lecoester, Irène Gaillard, Justine Forrierre, Francis Six   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Temporal Map of Coaching

Frontiers in Psychology, 2017
Economic pressures on companies, technological developments, and less stable career paths pose potential threats to the well-being of employees (e.g., stress, burn-out) and require constant adaptation.
Tim Theeboom, Annelies E. M. Van Vianen, Bianca Beersma   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source