Results 41 to 50 of about 1,568,884 (267)
As organizations increasingly adopt virtual and hybrid work models, understanding how psychological resources are developed in such settings is critical for fostering positive work cultures.
Rebekka Kuhlmann, Ingo Klingenberg
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The Role of Digital Transformation Mechanisms in Improving Services in NGOs [PDF]
The study aimed to identify the mechanisms of digital transformation and their role in improving services in NGOs. It focuses specifically on the obstacles facing the implementation of digital transformation mechanisms to improve services in NGOs and to ...
Riham Mostafa Abdelhameed Mohamed Al Johari
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Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
As a result of the Second Karabakh War in 2020, a significant number of children and adolescents in Azerbaijan experienced severe psycho-emotional difficulties, including post-traumatic stress disorder (PTSD), anxiety, and depression.
Aynur Bunyatova
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Does Telecare Improve Interorganisational Collaboration?
Introduction: Previous studies have suggested that telecare can improve interorganisational collaboration within fragmented health care systems, yet this outcome has not been examined in a large-scale setting.
Jannie Kristine Bang Christensen
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Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Crafting From Home: A Qualitative Analysis of Job Characteristics and Job Crafting in Hybrid Work
With the transition to hybrid work arrangements, employees experience altered job characteristics that increase the relevance of proactively shaping their work environment.
Katharina Sophie Apenbrink, Stefan Süß
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