Results 61 to 70 of about 15,382,807 (261)
OBJECTIVES: This study aimed to examine the contribution of employer characteristics to continued employment of employees with residual work capacity.
Raun van Ooijen +3 more
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Remote participation at JET Task Force work: users experience
The Joint European Torus (JET) fusion experiment is now operated with strong involvement of physicists from outside research laboratories, which often requires remote participation in JET physics experiments.
Farthing, J. +5 more
core +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Reimagining social work: letting go of futures past
Imminent crises and the much-needed transition to a sustainable society bring knowledge about de-implementation to the fore. Using case studies with inspiration from process tracing, and with tools from Charles Tilly’s theory on Durable inequality, we ...
Kristina Carlsson Stylianides +4 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
This study investigates cross-cultural differences in public perception of mobility electrification by applying natural language processing (NLP) techniques to social media discourse in Germany and China.
Kaplan Ugur Bulut, Hamid Mostofi
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Welfare to Work ; TANF work participation rates
"April 22, 1998."; Compares the work-related activities the state can fund with Welfare to Work (WTW) grants, the work-related activities that count toward the federal work participation rate under Temporary Assistance for Needy Families (TANF), the ...
Jordan, Laura (Laura J.),
core

