Results 181 to 190 of about 29,015,449 (345)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Optimizing work performance and engagement in adults with hearing loss: the role of hearing devices. [PDF]

open access: yesSci Rep
Lim S   +10 more
europepmc   +1 more source

The Individual Work Performance Questionnaire: Psychometric Properties of the Italian Version. [PDF]

open access: yesEur J Investig Health Psychol Educ, 2023
Platania S   +3 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Mindfulness-Based Programmes for Work Performance: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. [PDF]

open access: yesStress Health
Vainre M   +12 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Reallocating desk workers' sitting time to standing or stepping: associations with work performance. [PDF]

open access: yesOccup Med (Lond), 2023
Lin CY   +7 more
europepmc   +1 more source

Performance Management Work

open access: yesWIRTSCHAFTSINFORMATIK, 2014
Andreas Brunnert   +5 more
openaire   +2 more sources

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