Results 91 to 100 of about 1,099,627 (374)

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

On Secure Workflow Decentralisation on the Internet [PDF]

, 2010
Decentralised workflow management systems are a new research area, where most work to-date has focused on the system's overall architecture. As little attention has been given to the security aspects in such systems, we follow a security driven approach,
Adi Shamir, Anne Vinter Ratzer, Bae Eun Jung, Caroline Fontaine, Christian Cachin, Daniel Augot, Edward J. Lusk, Georgios John Fakas, Jianjie Zhao, Jun Yan, Kuo-Hsuan Huanga, L Harn, Leslie Lamport, Li Guo, Li Guo, Luke McDowell, Mark Miller, Nicholas Charles Russell, Patrick P. C. Lee, Petteri Kaskenpalo, Petteri Kaskenpalo, Pranay Chaudhuri, Rob Sherwood, RSA Laboratories, Tom Van Cutsem, Victor Shoup, W. M. P. Van Der Aalst, Wil M. P. van der Aalst, Wil M. P. van der Aalst   +28 more
core   +3 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Using Make for Reproducible and Parallel Neuroimaging Workflow and Quality Assurance

Frontiers in Neuroinformatics, 2016
The contribution of this paper is to describe how we can program neuroimaging workflow using Make, a software development tool designed for describing how to build executables from source files.
Mary K. Askren, Trevor K McAllister-Day, Natalie eKoh, Zoe eMestre, Jennifer N Dines, Benjamin A Korman, Susan J Melhorn, Daniel J Peterson, Matthew ePeverill, Xiaoyan eQin, Swati D Rane, Melissa A Reilly, Maya A Reiter, Kelly A Sambrook, Karl A Woelfer, Thomas J Grabowski, Tara M Madhyastha   +16 more
doaj   +1 more source

Planning with Global Constraints for Computing Infrastructure Reconfiguration [PDF]

, 2012
This paper presents a prototype system called SFplan- ner which uses an automated planning technique to generate workflows for reconfiguring a computing infras- tructure.
Anderson, Paul, Herry, Herry
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Sensitivity analysis of environmental models: A systematic review with practical workflow

Environmental Modelling & Software, 2014
Sensitivity Analysis (SA) investigates how the variation in the output of a numerical model can be attributed to variations of its input factors. SA is increasingly being used in environmental modelling for a variety of purposes, including uncertainty ...
F. Pianosi, K. Beven, J. Freer, J. Hall, J. Rougier, D. Stephenson, Thorsten Wagener   +6 more
semanticscholar   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

De novo clustering of long-read amplicons improves phylogenetic insight into microbiome data

Gut Microbes
Long-read amplicon profiling through read classification limits phylogenetic analysis of amplicons while community analysis of multicopy genes, relying on unique molecular identifier (UMI) corrections, often demands deep sequencing.
Yan Hui, Dennis Sandris Nielsen, Lukasz Krych   +2 more
doaj   +1 more source

From Raw Data to FAIR Data: The FAIRification Workflow for Health Research

Methods of Information in Medicine, 2020
Background FAIR (findability, accessibility, interoperability, and reusability) guiding principles seek the reuse of data and other digital research input, output, and objects (algorithms, tools, and workflows that led to that data) making them findable,
Ali Anil Sinaci, Francisco Núñez-Benjumea, M. Gencturk, M. Jauer, T. Deserno, C. Chronaki, Giorgio Cangioli, Carlos Cavero-Barca, Juan M Rodríguez-Pérez, Manuel M. Pérez-Pérez, Gokce Banu Laleci Erturkmen, Tony Hernández-Pérez, Eva Méndez-Rodríguez, C. Parra-Calderón   +13 more
semanticscholar   +1 more source