Results 31 to 40 of about 437,411 (211)

PyGNA: a unified framework for geneset network analysis

BMC Bioinformatics, 2020
Background Gene and protein interaction experiments provide unique opportunities to study the molecular wiring of a cell. Integrating high-throughput functional genomics data with this information can help identifying networks associated with complex ...
Viola Fanfani, Fabio Cassano, Giovanni Stracquadanio   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Datasets, Machine Learning Recognition Performance, and Key Issues in Nursing Care Activity Recognition: A Systematic Review

IEEE Access
Countries experiencing rapid aging face severe caregiver shortages, necessitating effective workforce optimization. Nursing care activity recognition (NCAR) offers a promising solution by automatically detecting caregiving tasks over time and visualizing
Yasuyuki Yoshida, Hiroyasu Miwa, Satoshi Nakae, Satoki Ogiso, Ryosuke Ichikari, Takashi Okuma   +5 more
doaj   +1 more source

RASflow: an RNA-Seq analysis workflow with Snakemake

BMC Bioinformatics, 2020
Background With the cost of DNA sequencing decreasing, increasing amounts of RNA-Seq data are being generated giving novel insight into gene expression and regulation.
Xiaokang Zhang, Inge Jonassen
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A BIM-based collaborative information framework for database integration in traditional building restoration: a case study

Journal of Asian Architecture and Building Engineering
Recent advancements in digital tools have facilitated the capture of precise data for traditional building restoration (TBR), while Building Information Modeling (BIM) offers structured information management and flexible 3D modeling for heritage ...
Chih-Han Kao, Wei-Tong Chen, Chung Kuang Ho   +2 more
doaj   +1 more source

Analysis and Comparison of Role-Based Interorganizational Workflows for a Construction Project

Applied Sciences, 2019
The implementation process of construction projects is an iterative process of continuous modification and improvement among participant organizations. Traditional workflow analysis methods for a single organization are not suitable for the analysis of ...
Jianlin Jiang, Jianguo Chen, Rongyue Zheng, Yan Zhou   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Systematic Benchmarking of 360° Virtual Reality Video Production: A Multi-Experiment Study of Encoding, Audio Systems, and Workflow

IEEE Access
Producing 360° virtual reality (VR) documentaries requires evidence about processing costs and deployment constraints. This study benchmarks five production stages using material from Beneath the Mist.
Banphot Nobaew, Nattapol Aunsri
doaj   +1 more source