Results 41 to 50 of about 506,139 (285)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

An overview of health workforce education and accreditation in Africa: implications for scaling-up capacity and quality

Human Resources for Health, 2022
Background For countries to achieve universal health coverage, they need to have well-functioning and resilient health systems. Achieving this requires a sufficient number of qualified health workers and this necessitates the importance of investments in
Sunny C. Okoroafor, Adam Ahmat, James Avoka Asamani, Jean Jacques Salvador Millogo, Jennifer Nyoni   +4 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Texas Workforce Investment Council Briefing Materials

, 2015
Briefing materials compiled for a meeting of the Texas Workforce Investment Council held March 6, 2015 in Room 201 of the Austin Community College Highland Business Center.
Texas Workforce Investment Council
core   +3 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

How do gender dynamics influence the preferences and decisions of an individual in selecting a technical and vocational education and training (TVET) program in Bhutan?

Journal of Innovation in Polytechnic Education
This research explores various factors that influence the preferences and decisions of women when selecting specific Technical and Vocational Education and Training (TVET) programs, focusing on individual interests, career prospects and employment ...
Tenzin Choden, Pemma Lhaden Lhendup, Sangay Dorji   +2 more
doaj   +1 more source

Correction to: Are the Global Strategic Directions for Strengthening Nursing and Midwifery 2016–2020 being implemented in countries? Findings from a cross-sectional analysis

Human Resources for Health, 2020
An amendment to this paper has been published and can be accessed via the original article.
Onyema Ajuebor, Carey McCarthy, Yin Li, Sumaya Mohamed Al-Blooshi, Nonhlanhla Makhanya, Giorgio Cometto   +5 more
doaj   +1 more source

Texas Workforce Commission: Labor News

, 1997
Quarterly newsletter of The Texas Workforce Commission's Labor News discussing employment news and updates for the ...
Texas Workforce Commission, Perdue, David R.   +1 more
core  

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source