Results 61 to 70 of about 202,421 (256)

Developing Compassionate Leadership in the UK in Healthcare Contexts: A Narrative Review of Leadership Programmes and Outcomes

Journal of Healthcare Leadership
Jonathan Minh Phuong,1 James Higgerson,1 Emma LT Pearce,1 Sarah C Willis,2 Ellen Ingrid Schafheutle1 1Centre for Pharmacy Workforce Studies, School of Health Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester, M13 ...
Phuong JM, Higgerson J, Pearce ELT, Willis SC, Schafheutle EI   +4 more
doaj  

A Loss Cycle of Burnout Symptoms and Reduced Coping Self-Efficacy: A Latent Change Score Modelling Approach

Chronic Stress
Police officers are frequently faced with chronic and acute stressors, such as excessive workload, organizational stressors and emotionally charged reports.
Liselotte M.J. Koning-Eikenhout, Roos Delahaij, Wim Kamphuis, Inge L. Hulshof, Joris Van Ruysseveldt   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Food pricing and consumer choice

Journal of Agriculture, Food Systems, and Community Development
Summary This policy and practice brief summarizes input from over 95 participants in the Fruit and Vege­table (Veggie) Policy Convening hosted by A Red Circle and University of Missouri Extension over two and a half days in February 2024. The purpose
Erica Williams, Participants of the 2024 Fruit and Vegetable Policy Convening, Lyndsey Ellis, Sagata Chatterjee, Thi Nguyen, Sarah Anderson   +5 more
doaj   +3 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Ready, Set, Coach: A Mixed Methods Pilot Study Exploring the Impact of Implementation Coaching to Optimize the Allied Health Assistant Workforce in Public Health Settings

Journal of Multidisciplinary Healthcare
Lucy Whelan,1 Sharon L McLean,1 Alexandra Edwards,1,2 Sandra Glagovski,1,2 Jessica Huglin,1 Janet E Golder,1,3 Abby M Foster1,2,4 1Allied Health Workforce Innovation, Strategy, Education & Research (WISER) Unit, Monash Health, Melbourne, VIC ...
Whelan L, McLean SL, Edwards A, Glagovski S, Huglin J, Golder JE, Foster AM   +6 more
doaj  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Thai Fathers’ Involvement in Childcare During Early Childhood: A Mixed-Methods Study

American Journal of Men's Health
This explanatory sequential mixed-methods study investigates the factors influencing Thai fathers’ involvement in early childhood Childcare. In the quantitative phase ( n  = 230), fathers’ involvement in Childcare was assessed using a Childcare ...
Atcharawadee Sriyasak, Chularat Howharn, Phatcharee Chookunhom, Varunee Ket-in, Atiya Sarakshetrin   +4 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source