Results 101 to 110 of about 4,218,234 (309)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Visualizing Set Relations and Cardinalities Using Venn and Euler Diagrams [PDF]
, 2013 In medicine, genetics, criminology and various other areas, Venn and Euler diagrams are used to visualize data set relations and their cardinalities.
Micallef, Luana
core
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
The expressiveness of spider diagrams augmented with constants [PDF]
, 2009 Spider diagrams are a visual language for expressing logical statements or constraints. Several sound and complete spider diagram systems have been developed and it has been shown that they are equivalent in expressive power to monadic first order logic ...
Howse, John +3 more
core +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Inductively Generating Euler Diagrams [PDF]
, 2011 Euler diagrams have a wide variety of uses, from information visualization to logical reasoning. In all of their application areas, the ability to automatically layout Euler diagrams brings considerable benefits.
Howse, John +3 more
core +1 more source
IEEE Access, 2019 Nowadays, rod pump is widely used in oilfield. Since most oil production equipment like pumping pumps are distributed in the wild, they are usually checked by manual inspection.
Jinze Liu, Jian Feng, Xianwen Gao
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Improving User Comprehension of Euler Diagrams [PDF]
, 2013 The graphical choices made when laying out Euler diagrams impact upon both aesthetic quality and comprehensiveness. Graphical choices include the shape, size and colour of closed curves which are commonly described as retinal variables to which we are ...
Howse, John +9 more
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source