Results 101 to 110 of about 347,531 (298)

Remote Work and the Psychosocial Work Environment: The Role of Contact

Nordic Journal of Working Life Studies
Remote work is fundamentally changing the organization of work, replacing the physical work environment of the office and creating a spatial distance between colleagues.
Mari Holm Ingelsrud, Vilde Hoff Bernstrøm, Wendy Nilsen   +2 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Hospital Mergers in Norway: Employee Health and Turnover to Three Destinations

Nordic Journal of Working Life Studies, 2017
This article investigates the probability of turnover to three destinations following hospital merg- ers: within the hospital sector, out of the hospital sector, and out of work.
Mari Holm Ingelsrud
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Paid Sick Leave as a Means to Reduce Sickness Presenteeism Among Physicians

Nordic Journal of Working Life Studies, 2017
Recurrent international data show that physicians often attend work while ill, termed sickness presenteeism. The current study investigated if sickness presenteeism scores among European physicians varied according to national paid sick leave legislation.
Ingrid Steen Rostad, Ann Fridner, Marie Gustafsson Sendén, Lise Tevik Løvseth   +3 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Work, Sickness, Absence, and Identity-Work

Nordic Journal of Working Life Studies, 2013
This article explores how a group of industrial workers experience long-term sickness absence and how they cope with this situation. The article presents data from in-depth interviews with male industrial workers employed in a Norwegian factory.
Trude Gjernes
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Organizational Support and Work Engagement: Onsite, Hybrid, and Remote Work during COVID-19

Nordic Journal of Working Life Studies
We analyzed the association of job autonomy, mental demands, and organizational support on work engagement and the moderating role of organizational support between mental demands and work engagement.
Kirsikka Selander, Tuomo Alasoini
doaj   +1 more source

Significance of Monitoring and Control for Employees’ Felt Trust, Motivation, and Mastery

Nordic Journal of Working Life Studies, 2017
The aim of the current study is to investigate the importance of monitoring and employee control for employees’ felt trust, as well as felt trust as a mediating variable between monitoring and control, intrinsic motivation and mastery. A random sample of
Vilde Hoff Bernstrøm, Helge Svare
doaj   +1 more source