Results 111 to 120 of about 56,587 (265)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reach and Recruitment of Microentrepreneurs: Lessons from a Finnish Health Promotion Intervention
Nordic Journal of Working Life Studies, 2022 Even though entrepreneurial work is stressful, health promotion interventions are seldom targeted at entrepreneurs, and we know little about how to reach and recruit this hard-to-reach group to such studies.
Jaana-Piia Mäkiniemi +10 more
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Measuring Subjective Wellbeing for Public Policy: Recommendations on Measures [PDF]
The measurement of wellbeing is central to public policy. There are three uses for any measure: 1) monitoring progress; 2) informing policy design; and 3) policy appraisal.
Richard Layard +2 more
core
Working Conditions and Wellbeing: A multilevel analysis of 34 European countries [PDF]
, 2014 This paper studies the effects of working conditions on wellbeing in 34 European countries. The background for the study is an interest in work as a social determinant of health, in this case mental health as captured in the concept of wellbeing ...
Stornes, Per
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Working in a demanding environment: employee wellbeing in secure forensic settings [PDF]
, 2016 Introduction: Care professionals suffering with poor wellbeing is a phenomenon that has been found to have a damaging effect upon individual employees, service users and organisations.
Cooper, Amelia
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Difference of perception of wellbeing level in the working environment employees and managers
, 2020 Wellbeing is a popular key term in professional and non-professional literature. Due to the widespread use of this term, it is possible to find different approaches to evaluating the level of wellbeing employees in an organization.
Konečný, František
core +1 more source