Results 101 to 110 of about 56,587 (265)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Professional wellbeing

, 2007
The aim of this chapter is to review issues relating to wellbeing and stress that may affect psychologists. It will discuss the causes of stress and wellbeing and the outcomes for psychologists, then set out some realistic ways in which stress can be ...
O’Driscoll, Michael P., Gardner, Dianne   +1 more
core  

Wellbeing Economics for the COVID-19 recovery: Ten principles to build back better

, 2020
The COVID-19 pandemic is having devastating effects on vulnerable communities around the world but we are also seeing glimpses of hope, where societies are working to “build back better” by ensuring basic needs and protecting our natural environment.
Garvey, Alice, Janoo, A, Corlet Walker, C, Hofferberth, Elena, Steinberger, J, Steinberger, Julia, Janoo, Amanda, O'Neill, D, Dyke, J, Bohnenberger, Katharina, Büchs, Milena, Dyke, James, Fritz, M, Elf, Patrick, O’Neill, Dan, Busch, J, Fanning, Andrew, Bohnenberger, K, Hardt, Lukas, Sahakian, Marlyne, Guillen-Royo, M, Ivanova, D, Baltruszewicz, M, Elf, P, Walker, Christine Corlet, Baltruszewicz, Marta, Trebeck, Katherine, Hofferberth, E, Trebeck, K, Sahakian, M, Garvey, A, Fanning, AL, Busch, Jonathan, Ivanova, Diana, Martin, Fritz, Guillen-Royo, Monica, Buchs, M, Hardt, L   +37 more
core  

Impacts of agile ways of working on wellbeing at work [PDF]

, 2021
Opinnäytetyön tavoitteena oli löytää ja ymmärtää ketterien menetelmien piirteitä, jotka ovat hyödyllistä tunnistaa työhöyvinvointia kehittäessä. Ketterät menetelmät sekä työhyvinvointi ovat ajankohtaisia teemoja arvioidessa yritysten kilpailukykyä niin ...
Metsäterä, Satu
core  

Organizational Initiatives for Promoting Employee Work-Life Reconciliation Over the Life Course. A Systematic Review of Intervention Studies

Nordic Journal of Working Life Studies, 2016
This review aimed to explore the initiatives, interventions, and experiments implemented by employing organizations and designed to support the work-life reconciliation at workplaces, and the effects of these actions on employees’ well-being at work.
Annina Ropponen, Marja Känsälä, Johanna Rantanen, Salla Toppinen-Tanner   +3 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Child Wellbeing in Two-Parent Families: How Do Characteristics and Relationships Matter? [PDF]

We use data from the Fragile Families and Child Wellbeing Study to examine the role of individual and family characteristics, as well as mother-father and parent-child relationships, with regard to differences in wellbeing for children living with their ...
Sara S. McLanahan, Lawrence M. Berger
core  

Are you happy at work? Unraveling the roles of social media usage, individual wellbeing and working environment [PDF]

, 2021
Employee happiness at workplace has been an increasingly popular topic among researchers and scholars in the past two decades due to the rise concern on its role as one of the contributing factors to the positive outcomes in organizations.
A.Manaf, Aini Maznina, Tengku Mohd Azzman, Tengku Siti Aisha, Idid, Syed Arabi   +2 more
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source