Results 151 to 160 of about 5,581,186 (359)
Working fluid selection of Organic Rankine Cycles
Energy Reports, 2020 H. Herath +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Evaluation of Soluble Oil vs. Semi Synthetic Metal Working Fluids at Toolamation Inc. [PDF]
Toolamation Inc. collaborated with technical assistance specialists from the Illinois Sustainable Technology Center (ISTC) to evaluate the metal working fluid (MWF) oil removal system and soluble-oil vs.
Boyle, Malcolm
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
ProcessesTo circumvent the numerous deficiencies inherent to water-based fracturing fluids and the associated greenhouse effect, CO2 fracturing fluids are employed as a novel reservoir working fluid for reservoir reconstruction in unconventional oil fields ...
Qiang Li +5 more
semanticscholar +1 more source
The SCSE Organic Rankine engine [PDF]
, 1981 The engine is the heart of a Power Conversion Subsystem (PCS) located at the focal point of a sun-tracking parabolic dish concentrator. The ORC engine employs a single-stage axial-flow turbine driving a high speed alternator to produce up to 25 kW ...
Boda, F. P.
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Working memory and fluid intelligence
, 2013 We are on the cusp of a new revolution in intelligence that affects every aspect of our lives from work and relationships, to our childhood, education, and old age. Working Memory, the ability to remember and mentally process information, is so important that without it we could not function as a society or as individuals.
Conway, A +2 more
openaire +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source