Results 171 to 180 of about 7,820,715 (391)

Paid and unpaid working hours among Swedish men and women in relation to depressive symptoms [PDF]

open access: bronze, 2017
Hugo Westerlund   +2 more
openalex   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Jornada de trabalho: o exemplo europeu
Hours of work: the European example
[PDF]

open access: yesNova Economia, 2000
This paper examines the role played by the decline in average annual hours of work per person in employment over the behavior of unemployment rate in Europe since II World War.
Fernando Augusto M. de Mattos
doaj  

Becoming a psychiatrist in Europe: the title is recognized across the European Union, but what are the differences in training, salary and working hours? [PDF]

open access: bronze, 2015
Franziska Baessler   +9 more
openalex   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

IMPACT OF LONG WORKING HOURS ON WOMEN’S SOCIOECONOMIC EMPOWERMENT

open access: yesCostos y Gestión, 2020
Due to continuous and rapid technological, cultural, and economic changes in the banking sector in specific, the need of working for long hours has increased dramatically among bankers especially after the economic crisis of 2008, which put bankers ...
Sajida El Othman
doaj  

Working Hour Arrangements and Working Hours A Microeconometric Analysis Based on German Time Diary Data [PDF]

open access: yes
The labour market providing individual resources and economic well-being is still a topic in the economic and social policy discussion. In the course of time the traditional full-time work is diminishing, new labour arrangements are discussed (keyword ...
Burgert, Derik, Merz, Joachim
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Fatores determinantes da atividade dos motoristas de caminhão e repercussões à saúde: um olhar a partir da análise coletiva do trabalho

open access: yesRevista Brasileira de Saúde Ocupacional
Este estudo tem o intuito de caracterizar a atividade do motorista de caminhão quanto à demanda do trabalho e aos desafios impostos pela sua organização do trabalho.
Claudia Roberta de Castro Moreno   +1 more
doaj   +1 more source

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