Results 91 to 100 of about 5,759,613 (298)

Wealth mobility and dynamics over entire individual working life cycles [PDF]

open access: yes
We study taxable wealth in unique Swedish administrative data, annually following a large sample of households over a period of almost 40 years. The main data limitation is non-observability of wealth for those below the tax exemption level. This implies
Hochguertel, Stefan, Ohlsson, Henry
core  

Psychosocial impact of visual impairment in working age adults [PDF]

open access: yes, 2009
This is an open access article - Copyright @ 2010 BMJ Publishing GroupAim: To review the evidence for the presence of lower levels of psychosocial well-being in working-age adults with visual impairment and for interventions to improve such levels of ...
Gosney, MA, Nyman, SR, Victor, CR
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

How Gender Conscious Pedagogy in Higher Education Can Stimulate Actions of Social Justice in Society

open access: yesSocial Inclusion, 2014
In order to reflect about methods that can generate social justice and democratization, this article emphasises on practical implementations, connected to gender conscious pedagogy.
Ann-Katrin Witt, Marta Cuesta
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Tipping the balance: the problematic nature of work–life balance in a low-income neighbourhood. [PDF]

open access: yes
The article attempts to locate the contested notion of work–life balance within the context of global trends and recent policy developments. It describes a small-scale qualitative study of work–life balance as it is experienced within a low-income ...
Dean, Hartley
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Capturing impacts of Leader and of measures to improve Quality of Life in rural areas [PDF]

open access: yes
The Helpdesk of European Evaluation Network for Rural Development supported by a group of external experts has prepared a Working Paper on ”Capturing the impacts of Leader and measures to improve the Quality of life (QoL) in rural areas”.
Brakalova, Marina   +14 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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