Results 41 to 50 of about 1,038,874 (251)

Intensive Working Memory Training Produces Functional Changes in Large-scale Frontoparietal Networks [PDF]

, 2016
Working memory is central to human cognition, and intensive cognitive training has been shown to expand working memory capacity in a given domain.
Gabrieli, John D. E., Thompson, Todd Wesley, Waskom, Michael L.   +2 more
core   +1 more source

Computerized training of non-verbal reasoning and working memory in children with intellectual disability

Frontiers in Human Neuroscience, 2012
Children with intellectual disabilities show deficits in both reasoning ability and working memory (WM) that impact everyday functioning and academic achievement.
Stina eSöderqvist, Sissela eBergman Nutley, Jon eOttersen, Katja Maria eGrill, Torkel eKlingberg   +4 more
doaj   +1 more source

Working Memory Training for Healthy Older Adults: The Role of Individual Characteristics in Explaining Short- and Long-Term Gains [PDF]

, 2017
Objective: The aim of the present study was to explore whether individual characteristics such as age, education, vocabulary, and baseline performance in a working memory (WM) task\u2014similar to the one used in the training (criterion task ...
Borella, Erika, Carbone, Elena, Carretti, Barbara, De Beni, Rossana, Pastore, Massimiliano   +4 more
core   +1 more source

The Impact of Auditory Working Memory Training on the Fronto-Parietal Working Memory Network

Frontiers in Human Neuroscience, 2012
Working memory training has been widely used to investigate working memory processes. We have shown previously that visual working memory benefits only from intra-modal visual but not from across-modal auditory working memory training.
Julia eSchneiders, Bertram eOpitz, Huijun eTang, Yuan eDeng, Chiaoxiang eXie, Hong eLi, Axel eMecklinger   +6 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Cultural differences in complex addition: efficient Chinese versus adaptive Belgians and Canadians [PDF]

, 2009
In the present study, the authors tested the effects of working-memory load on math problem solving in 3 different cultures: Flemish-speaking Belgians, English-speaking Canadians, and Chinese-speaking Chinese currently living in Canada.
Imbo, Ineke, LeFevre, Jo-Anne
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

A Review of Working Memory Training in the Management of Attention Deficit Hyperactivity Disorder

Frontiers in Behavioral Neuroscience, 2021
Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders among children. Working memory deficits underlie many of the behavioural symptoms of ADHD. Alongside psychostimulant medications, strategies to improve
Maha Saleh Habsan Al-Saad, Maha Saleh Habsan Al-Saad, Basma Al-Jabri, Abeer F. Almarzouki   +3 more
doaj   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source