Results 101 to 110 of about 1,232,429 (290)

Team Work in Protein Processing

open access: yesChemistry & Biology, 2007
MetAP substrates and their physiological roles have remained elusive. In this issue of Chemistry & Biology, Hu and colleagues [1] employ a small molecule approach to study the impact of MetAP inhibition on the molecular regulation and cellular functions of the proto-oncogene c-Src.
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

LIVING THE SUFFERING AND CHALLENGES IN THE WORK: SELF-CRITICAL OPINIONS OF A NURSE-EDUCATORS GROUP [PDF]

open access: yesRevista Eletrônica de Enfermagem, 2004
This is a cutting of my máster, thisI had as objective to know the nurses-educators self-criticalexpressions concerning the working process on professional teaching for technical nursing.
Marta Lenise do Prado   +1 more
doaj  

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Good Corporate Governance and Working Conditions at Petrol Stations: A Critical Political Economy Perspective

open access: yesJSP: Jurnal Ilmu Sosial dan Ilmu Politik
This study examines the claim that the benefits of good corporate governance (GCG) extend to all stakeholders, with a specific focus on the advantages for workers during operational processes.
Ardiyansyah Ardiyansyah
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Work processes - A work in process - Building a new work processes PSF for Petro-HRA

open access: yes, 2015
This master thesis examines management support and safety culture in order to create a suggestion for a new PSF in Petro-HRA. Building on SPAR-H, the work processes PSF is examined and two select factors, management support and safety culture, are chosen for review.
openaire   +1 more source

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