Results 61 to 70 of about 333,323 (263)

Sculptural Images of Yakushi Nyorai

Ежегодник Япония, 2022
Yakushi Nyorai figures form the central theme of the present work, which introduces superb creations of Asuka, Nara, Heian sculptors that survive in our days in the temples of ancient capitals of Japan.
Y. Kuzhel
doaj  

Porcelain Prototypes: Attributing the Models of Ural Art Iron Casting

Известия Уральского федерального университета. Серия 2: Гуманитарные науки, 2018
This article considers one of the most relevant issues in the study of art casting from cast iron. Due to the fact that the administration and owners of the Kasli Iron Works responded in their strategies to the tastes of different consumers and also ...
Kseniya Aleksandrovna Gileva
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

“I Have All the Time in the World”: Bernadette Mayer’s Being in Time

Humanities
This essay argues that several of Bernadette Mayer’s major works foreground and develop experiences of subjective time as moments of resistance to the standardizing force of objective clock and calendric time that governs daily material existence. Basing
Amy Moorman Robbins
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

The analysis of Historical Experience of Activity of Bodies of the Public and Military Administration in the Solution of Problems of Modernization of Artillery of Red army in the 1930th years

Управленческое консультирование, 2018
In the article on the basis of the analysis and synthesis of archival documents of materials,earlier inaccessible to a wide range of the readers of scientific works, activities of bodies of the public and military administration for modernization of ...
Alexander Ivanovich Lushin, Victor Andreevich Chernukhin, Yury Vadimovich Scherbakov   +2 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Introduction: In Search of Digital Feminisms

Lateral, 2013
Edited by Katherine Behar and Silvia Ruzanka, In Search of Digital Feminisms includes five essays and the editors’ introduction that suggests we play with the shift from surfing to searching to what is fast becoming the offer, if not the intrusion, of ...
Patricia Ticineto Clough
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source