Results 91 to 100 of about 4,826,840 (386)

Assessing the impact of the introduction of the World Health Organization growth standards and weight-for-height z-score criterion on the response to treatment of severe acute malnutrition in children: Secondary data analysis [PDF]

, 2009
OBJECTIVE: The objective of our study was to assess the impact of adopting the World Health Organization growth standards and weight-for-height z-score criterion on the response to treatment of severe acute malnutrition in children compared with the use ...
Grais, R, Isanaka, S, Shepherd, S, Villamor, E   +3 more
core   +2 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Reaching the global tuberculosis control targets in the Western Pacific Region

Bulletin of the World Health Organization
PROBLEM: In 1999, a tuberculosis (TB) crisis was declared in the Western Pacific Region. APPROACH: In response, WHO established the Stop TB Special Project, which sought to halve 2000 levels of TB prevalence and mortality by 2010 through first reaching ...
Pieter van Maaren, Bernard Tomas, Philippe Glaziou, Takeshi Kasai, Dongil Ahn   +4 more
doaj   +1 more source

Prevalence of Antibiotic Resistance in Helicobacter pylori: A Systematic Review and Meta-analysis in World Health Organization Regions.

Gastroenterology, 2018
BACKGROUND & AIMS In 2017, the World Health Organization (WHO) designated clarithromycin-resistant Helicobacter pylori a high priority for antibiotic research and development.
A. Savoldi, E. Carrara, D. Graham, M. Conti, E. Tacconelli   +4 more
semanticscholar   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Measuring maternal mortality : an overview of opportunities and options for developing countries [PDF]

, 2008
Background:There is currently an unprecedented expressed need and demand for estimates of maternal mortality in developing countries. This has been stimulated in part by the creation of a Millennium Development Goal that will be judged partly on the ...
A Paxton, AP MacKay, C AbouZahr, C Chandra-Sekar, C Hunger, C Ronsmans, C Ronsmans, C Stanton, C Stanton, C Stanton, CJ Murray, CL Abou-Zahr, D Chandromahan, E Fottrell, E Gakidou, F Binka, J Shiffman, K Hill, K Hill, K Hill, Ministry of Health and Population, Egypt, N Rutenberg, N Walker, O Campbell, OMR Campbell, OMR Campbell, PD Ghys, PW Setel, S Ahmed, S Ahmed, SC Amstrup, T Boerma, T Wardlaw, UNICEF, WHO, UNFPA, United Nations, V Fauveau, W Brass, WJ Graham, WJ Graham, WJ Graham, WJ Graham, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization/UNICEF   +46 more
core   +5 more sources

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Migration of health-care workers from developing countries: strategic approaches to its management

Bulletin of the World Health Organization, 2004
Of the 175 million people (2.9% of the world's population) living outside their country of birth in 2000, 65 million were economically active. The rise in the number of people migrating is significant for many developing countries because they are losing
Barbara Stilwell, Khassoum Diallo, Pascal Zurn, Marko Vujicic, Orvill Adams, Mario Dal Poz   +5 more
doaj  

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

CBR: A Strategy for Rehabilitation, Equalization of Opportunities, Poverty Reduction and, Social Inclusion of People With Disabilities [PDF]

, 2004
[From Introduction] Community-based rehabilitation (CBR) promotes collaboration among community leaders, people with disabilities, their families,and other concerned citizens to provide equal opportunities for all people with disabilities in the ...
International Labour Organization, United Nations Educational, Scientific and Cultural Organization, World Health Organization   +2 more
core   +1 more source